TY - STD TI - GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1545-1602. ID - ref1 ER - TY - JOUR AU - Listl, S. AU - Galloway, J. AU - Mossey, P. A. AU - Marcenes, W. PY - 2015 DA - 2015// TI - Global economic impact of dental diseases JO - J Dent Res VL - 94 UR - https://doi.org/10.1177/0022034515602879 DO - 10.1177/0022034515602879 ID - Listl2015 ER - TY - JOUR AU - Duran-Pinedo, A. E. AU - Frias-Lopez, J. PY - 2015 DA - 2015// TI - Beyond microbial community composition: functional activities of the oral microbiome in health and disease JO - Microbes Infect VL - 17 UR - https://doi.org/10.1016/j.micinf.2015.03.014 DO - 10.1016/j.micinf.2015.03.014 ID - Duran-Pinedo2015 ER - TY - JOUR AU - Takahashi, N. AU - Nyvad, B. PY - 2016 DA - 2016// TI - Ecological hypothesis of dentin and root caries JO - Caries Res VL - 50 UR - https://doi.org/10.1159/000447309 DO - 10.1159/000447309 ID - Takahashi2016 ER - TY - JOUR AU - Almeida Pdel, V. AU - Gregio, A. M. AU - Machado, M. A. AU - Lima, A. A. AU - Azevedo, L. R. PY - 2008 DA - 2008// TI - Saliva composition and functions: a comprehensive review JO - J Contemp Dent Pract VL - 9 UR - https://doi.org/10.5005/jcdp-9-3-72 DO - 10.5005/jcdp-9-3-72 ID - Almeida Pdel2008 ER - TY - JOUR AU - Nieuw Amerongen, A. AU - Bolscher, J. G. AU - Veerman, E. C. PY - 2004 DA - 2004// TI - Salivary proteins: protective and diagnostic value in cariology? JO - Caries Res VL - 38 UR - https://doi.org/10.1159/000077762 DO - 10.1159/000077762 ID - Nieuw Amerongen2004 ER - TY - JOUR AU - Marsh, P. D. PY - 1994 DA - 1994// TI - Microbial ecology of dental plaque and its significance in health and disease JO - Adv Dent Res VL - 8 UR - https://doi.org/10.1177/08959374940080022001 DO - 10.1177/08959374940080022001 ID - Marsh1994 ER - TY - JOUR AU - Kleinberg, I. PY - 2002 DA - 2002// TI - A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis JO - Crit Rev Oral Biol Med VL - 13 UR - https://doi.org/10.1177/154411130201300202 DO - 10.1177/154411130201300202 ID - Kleinberg2002 ER - TY - JOUR AU - Takahashi, N. AU - Nyvad, B. PY - 2008 DA - 2008// TI - Caries ecology revisited: microbial dynamics and the caries process JO - Caries Res VL - 42 UR - https://doi.org/10.1159/000159604 DO - 10.1159/000159604 ID - Takahashi2008 ER - TY - JOUR AU - Hemadi, A. S. AU - Huang, R. AU - Zhou, Y. AU - Zou, J. PY - 2017 DA - 2017// TI - Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment JO - Int J Oral Sci VL - 9 UR - https://doi.org/10.1038/ijos.2017.35 DO - 10.1038/ijos.2017.35 ID - Hemadi2017 ER - TY - JOUR AU - Koscielniak, D. AU - Jurczak, A. AU - Zygmunt, A. AU - Krzysciak, W. PY - 2012 DA - 2012// TI - Salivary proteins in health and disease JO - Acta Biochim Pol VL - 59 UR - https://doi.org/10.18388/abp.2012_2077 DO - 10.18388/abp.2012_2077 ID - Koscielniak2012 ER - TY - JOUR AU - Camelo-Castillo, A. J. AU - Mira, A. AU - Pico, A. AU - Nibali, L. AU - Henderson, B. AU - Donos, N. AU - Tomas, I. PY - 2015 DA - 2015// TI - Subgingival microbiota in health compared to periodontitis and the influence of smoking JO - Front Microbiol VL - 6 UR - https://doi.org/10.3389/fmicb.2015.00119 DO - 10.3389/fmicb.2015.00119 ID - Camelo-Castillo2015 ER - TY - JOUR AU - Ren, W. AU - Zhang, Q. AU - Liu, X. AU - Zheng, S. AU - Ma, L. AU - Chen, F. AU - Xu, T. AU - Xu, B. PY - 2017 DA - 2017// TI - Exploring the oral microflora of preschool children JO - J Microbiol VL - 55 UR - https://doi.org/10.1007/s12275-017-6474-8 DO - 10.1007/s12275-017-6474-8 ID - Ren2017 ER - TY - JOUR AU - Zhang, M. AU - Chen, Y. AU - Xie, L. AU - Li, Y. AU - Jiang, H. AU - Du, M. PY - 2015 DA - 2015// TI - Pyrosequencing of plaque microflora in twin children with discordant caries phenotypes JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0141310 DO - 10.1371/journal.pone.0141310 ID - Zhang2015 ER - TY - JOUR AU - Treumann, A. AU - Thiede, B. PY - 2010 DA - 2010// TI - Isobaric protein and peptide quantification: perspectives and issues JO - Expert Rev Proteomics VL - 7 UR - https://doi.org/10.1586/epr.10.29 DO - 10.1586/epr.10.29 ID - Treumann2010 ER - TY - JOUR AU - Wang, K. AU - Wang, X. AU - Zheng, S. AU - Niu, Y. AU - Zheng, W. AU - Qin, X. AU - Li, Z. AU - Luo, J. AU - Jiang, W. AU - Zhou, X. PY - 2018 DA - 2018// TI - iTRAQ-based quantitative analysis of age-specific variations in salivary proteome of caries-susceptible individuals JO - J Transl Med VL - 16 UR - https://doi.org/10.1186/s12967-018-1669-2 DO - 10.1186/s12967-018-1669-2 ID - Wang2018 ER - TY - STD TI - Jiang S, Gao X, Jin L, Lo EC. Salivary Microbiome Diversity in Caries-Free and Caries-Affected Children. Int J Mol Sci. 2016;17(12):1978. ID - ref17 ER - TY - JOUR AU - Xiao, C. AU - Ran, S. AU - Huang, Z. AU - Liang, J. PY - 2016 DA - 2016// TI - Bacterial diversity and community structure of Supragingival plaques in adults with dental health or caries revealed by 16S pyrosequencing JO - Front Microbiol VL - 7 ID - Xiao2016 ER - TY - JOUR AU - Zhou, J. AU - Jiang, N. AU - Wang, S. AU - Hu, X. AU - Jiao, K. AU - He, X. AU - Li, Z. AU - Wang, J. PY - 2016 DA - 2016// TI - Exploration of human salivary microbiomes--insights into the novel characteristics of microbial community structure in caries and caries-free subjects JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0147039 DO - 10.1371/journal.pone.0147039 ID - Zhou2016 ER - TY - JOUR AU - Morris, R. M. AU - Nunn, B. L. AU - Frazar, C. AU - Goodlett, D. R. AU - Ting, Y. S. AU - Rocap, G. PY - 2010 DA - 2010// TI - Comparative metaproteomics reveals ocean-scale shifts in microbial nutrient utilization and energy transduction JO - ISME J VL - 4 UR - https://doi.org/10.1038/ismej.2010.4 DO - 10.1038/ismej.2010.4 ID - Morris2010 ER - TY - JOUR AU - Chen, H. AU - Jiang, W. PY - 2014 DA - 2014// TI - Application of high-throughput sequencing in understanding human oral microbiome related with health and disease JO - Front Microbiol VL - 5 ID - Chen2014 ER - TY - JOUR AU - Pruesse, E. AU - Quast, C. AU - Knittel, K. AU - Fuchs, B. M. AU - Ludwig, W. AU - Peplies, J. AU - Glockner, F. O. PY - 2007 DA - 2007// TI - SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB JO - Nucleic Acids Res VL - 35 UR - https://doi.org/10.1093/nar/gkm864 DO - 10.1093/nar/gkm864 ID - Pruesse2007 ER - TY - JOUR AU - Schloss, P. D. AU - Westcott, S. L. AU - Ryabin, T. AU - Hall, J. R. AU - Hartmann, M. AU - Hollister, E. B. AU - Lesniewski, R. A. AU - Oakley, B. B. AU - Parks, D. H. AU - Robinson, C. J. PY - 2009 DA - 2009// TI - Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities JO - Appl Environ Microbiol VL - 75 UR - https://doi.org/10.1128/AEM.01541-09 DO - 10.1128/AEM.01541-09 ID - Schloss2009 ER - TY - JOUR AU - Segata, N. AU - Izard, J. AU - Waldron, L. AU - Gevers, D. AU - Miropolsky, L. AU - Garrett, W. S. AU - Huttenhower, C. PY - 2011 DA - 2011// TI - Metagenomic biomarker discovery and explanation JO - Genome Biol VL - 12 UR - https://doi.org/10.1186/gb-2011-12-6-r60 DO - 10.1186/gb-2011-12-6-r60 ID - Segata2011 ER - TY - JOUR AU - Hurley, E. AU - Barrett, M. P. J. AU - Kinirons, M. AU - Whelton, H. AU - Ryan, C. A. AU - Stanton, C. AU - Harris, H. M. B. AU - O'Toole, P. W. PY - 2019 DA - 2019// TI - Comparison of the salivary and dentinal microbiome of children with severe-early childhood caries to the salivary microbiome of caries-free children JO - BMC Oral Health VL - 19 UR - https://doi.org/10.1186/s12903-018-0693-1 DO - 10.1186/s12903-018-0693-1 ID - Hurley2019 ER - TY - JOUR AU - Jiang, Q. AU - Liu, J. AU - Chen, L. AU - Gan, N. AU - Yang, D. PY - 2018 DA - 2018// TI - The Oral microbiome in the elderly with dental caries and health JO - Front Cell Infect Microbiol VL - 8 UR - https://doi.org/10.3389/fcimb.2018.00442 DO - 10.3389/fcimb.2018.00442 ID - Jiang2018 ER - TY - JOUR AU - Xu, P. AU - Gunsolley, J. PY - 2014 DA - 2014// TI - Application of metagenomics in understanding oral health and disease JO - Virulence VL - 5 UR - https://doi.org/10.4161/viru.28532 DO - 10.4161/viru.28532 ID - Xu2014 ER - TY - JOUR AU - McLean, J. S. PY - 2014 DA - 2014// TI - Advancements toward a systems level understanding of the human oral microbiome JO - Front Cell Infect Microbiol VL - 4 ID - McLean2014 ER - TY - JOUR AU - Wade, W. G. PY - 2013 DA - 2013// TI - The oral microbiome in health and disease JO - Pharmacol Res VL - 69 UR - https://doi.org/10.1016/j.phrs.2012.11.006 DO - 10.1016/j.phrs.2012.11.006 ID - Wade2013 ER - TY - JOUR AU - Xin, B. C. AU - Luo, A. H. AU - Qin, J. AU - Paster, B. J. AU - Xu, Y. L. AU - Li, Y. L. AU - Yang, D. Q. PY - 2013 DA - 2013// TI - Microbial diversity in the oral cavity of healthy Chinese Han children JO - Oral Dis VL - 19 UR - https://doi.org/10.1111/odi.12018 DO - 10.1111/odi.12018 ID - Xin2013 ER - TY - JOUR AU - Luo, A. H. AU - Yang, D. Q. AU - Xin, B. C. AU - Paster, B. J. AU - Qin, J. PY - 2012 DA - 2012// TI - Microbial profiles in saliva from children with and without caries in mixed dentition JO - Oral Dis VL - 18 UR - https://doi.org/10.1111/j.1601-0825.2012.01915.x DO - 10.1111/j.1601-0825.2012.01915.x ID - Luo2012 ER - TY - JOUR AU - Xu, H. AU - Hao, W. AU - Zhou, Q. AU - Wang, W. AU - Xia, Z. AU - Liu, C. AU - Chen, X. AU - Qin, M. AU - Chen, F. PY - 2014 DA - 2014// TI - Plaque bacterial microbiome diversity in children younger than 30 months with or without caries prior to eruption of second primary molars JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0089269 DO - 10.1371/journal.pone.0089269 ID - Xu2014 ER - TY - JOUR AU - Xu, Y. AU - Jia, Y. H. AU - Chen, L. AU - Huang, W. M. AU - Yang, D. Q. PY - 2018 DA - 2018// TI - Metagenomic analysis of oral microbiome in young children aged 6-8 years living in a rural isolated Chinese province JO - Oral Dis VL - 24 UR - https://doi.org/10.1111/odi.12871 DO - 10.1111/odi.12871 ID - Xu2018 ER - TY - JOUR AU - Ling, Z. AU - Kong, J. AU - Jia, P. AU - Wei, C. AU - Wang, Y. AU - Pan, Z. AU - Huang, W. AU - Li, L. AU - Chen, H. AU - Xiang, C. PY - 2010 DA - 2010// TI - Analysis of oral microbiota in children with dental caries by PCR-DGGE and barcoded pyrosequencing JO - Microb Ecol VL - 60 UR - https://doi.org/10.1007/s00248-010-9712-8 DO - 10.1007/s00248-010-9712-8 ID - Ling2010 ER - TY - JOUR AU - Takahashi, N. AU - Nyvad, B. PY - 2011 DA - 2011// TI - The role of bacteria in the caries process: ecological perspectives JO - J Dent Res VL - 90 UR - https://doi.org/10.1177/0022034510379602 DO - 10.1177/0022034510379602 ID - Takahashi2011 ER - TY - JOUR AU - Marsh, P. D. PY - 2006 DA - 2006// TI - Dental plaque as a biofilm and a microbial community - implications for health and disease JO - BMC Oral Health VL - 6 UR - https://doi.org/10.1186/1472-6831-6-S1-S14 DO - 10.1186/1472-6831-6-S1-S14 ID - Marsh2006 ER - TY - JOUR AU - Selwitz, R. H. AU - Ismail, A. I. AU - Pitts, N. B. PY - 2007 DA - 2007// TI - Dental caries JO - Lancet (London, England) VL - 369 UR - https://doi.org/10.1016/S0140-6736(07)60031-2 DO - 10.1016/S0140-6736(07)60031-2 ID - Selwitz2007 ER - TY - JOUR AU - Zhu, B. AU - Macleod, L. C. AU - Kitten, T. AU - Xu, P. PY - 2018 DA - 2018// TI - Streptococcus sanguinis biofilm formation & interaction with oral pathogens JO - Future Microbiol VL - 13 UR - https://doi.org/10.2217/fmb-2018-0043 DO - 10.2217/fmb-2018-0043 ID - Zhu2018 ER - TY - JOUR AU - Philip, N. AU - Suneja, B. AU - Walsh, L. PY - 2018 DA - 2018// TI - Beyond Streptococcus mutans: clinical implications of the evolving dental caries aetiological paradigms and its associated microbiome JO - Br Dent J VL - 224 UR - https://doi.org/10.1038/sj.bdj.2018.81 DO - 10.1038/sj.bdj.2018.81 ID - Philip2018 ER - TY - JOUR AU - Peyyala, R. AU - Ebersole, J. L. PY - 2013 DA - 2013// TI - Multispecies biofilms and host responses: "discriminating the trees from the forest" JO - Cytokine VL - 61 UR - https://doi.org/10.1016/j.cyto.2012.10.006 DO - 10.1016/j.cyto.2012.10.006 ID - Peyyala2013 ER - TY - JOUR AU - Mark Welch, J. L. AU - Rossetti, B. J. AU - Rieken, C. W. AU - Dewhirst, F. E. AU - Borisy, G. G. PY - 2016 DA - 2016// TI - Biogeography of a human oral microbiome at the micron scale JO - Proc Natl Acad Sci U S A VL - 113 UR - https://doi.org/10.1073/pnas.1522149113 DO - 10.1073/pnas.1522149113 ID - Mark Welch2016 ER - TY - JOUR AU - Zaura, E. AU - Keijser, B. J. AU - Huse, S. M. AU - Crielaard, W. PY - 2009 DA - 2009// TI - Defining the healthy "core microbiome" of oral microbial communities JO - BMC Microbiol VL - 9 UR - https://doi.org/10.1186/1471-2180-9-259 DO - 10.1186/1471-2180-9-259 ID - Zaura2009 ER - TY - JOUR AU - Turnbaugh, P. J. AU - Gordon, J. I. PY - 2009 DA - 2009// TI - The core gut microbiome, energy balance and obesity JO - J Physiol VL - 587 UR - https://doi.org/10.1113/jphysiol.2009.174136 DO - 10.1113/jphysiol.2009.174136 ID - Turnbaugh2009 ER - TY - JOUR AU - Huse, S. M. AU - Ye, Y. AU - Zhou, Y. AU - Fodor, A. A. PY - 2012 DA - 2012// TI - A core human microbiome as viewed through 16S rRNA sequence clusters JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0034242 DO - 10.1371/journal.pone.0034242 ID - Huse2012 ER - TY - JOUR AU - Li, K. AU - Bihan, M. AU - Methe, B. A. PY - 2013 DA - 2013// TI - Analyses of the stability and core taxonomic memberships of the human microbiome JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0063139 DO - 10.1371/journal.pone.0063139 ID - Li2013 ER - TY - JOUR AU - Yan, G. AU - Huang, W. AU - Xue, H. AU - Jia, Y. AU - Yang, D. PY - 2014 DA - 2014// TI - Relationship between dental caries and salivary proteome by electrospray ionization ion-trap tandem mass spectrometry in children aged 6 to 8 years JO - Hua Xi Kou Qiang Yi Xue Za Zhi VL - 32 ID - Yan2014 ER - TY - JOUR AU - Fine, D. H. AU - Toruner, G. A. AU - Velliyagounder, K. AU - Sampathkumar, V. AU - Godboley, D. AU - Furgang, D. PY - 2013 DA - 2013// TI - A lactotransferrin single nucleotide polymorphism demonstrates biological activity that can reduce susceptibility to caries JO - Infect Immun VL - 81 UR - https://doi.org/10.1128/IAI.01063-12 DO - 10.1128/IAI.01063-12 ID - Fine2013 ER - TY - JOUR AU - Hong, S. W. AU - Seo, D. G. AU - Baik, J. E. AU - Cho, K. AU - Yun, C. H. AU - Han, S. H. PY - 2014 DA - 2014// TI - Differential profiles of salivary proteins with affinity to Streptococcus mutans lipoteichoic acid in caries-free and caries-positive human subjects JO - Mol Oral Microbiol VL - 29 UR - https://doi.org/10.1111/omi.12057 DO - 10.1111/omi.12057 ID - Hong2014 ER - TY - JOUR AU - Ballal, V. AU - Rao, S. AU - Bagheri, A. AU - Bhat, V. AU - Attin, T. AU - Zehnder, M. PY - 2017 DA - 2017// TI - MMP-9 in dentinal fluid correlates with caries lesion depth JO - Caries Res VL - 51 UR - https://doi.org/10.1159/000479040 DO - 10.1159/000479040 ID - Ballal2017 ER - TY - JOUR AU - Moslemi, M. AU - Sattari, M. AU - Kooshki, F. AU - Fotuhi, F. AU - Modarresi, N. AU - Khalili Sadrabad, Z. AU - Shadkar, M. S. PY - 2015 DA - 2015// TI - Relationship of salivary Lactoferrin and lysozyme concentrations with early childhood caries JO - J Dent Res Dental Clin Dent Prospects VL - 9 UR - https://doi.org/10.15171/joddd.2015.022 DO - 10.15171/joddd.2015.022 ID - Moslemi2015 ER - TY - JOUR AU - Jenssen, H. AU - Hancock, R. E. PY - 2009 DA - 2009// TI - Antimicrobial properties of lactoferrin JO - Biochimie VL - 91 UR - https://doi.org/10.1016/j.biochi.2008.05.015 DO - 10.1016/j.biochi.2008.05.015 ID - Jenssen2009 ER - TY - JOUR AU - Mazzoni, A. AU - Tjaderhane, L. AU - Checchi, V. AU - Lenarda, R. AU - Salo, T. AU - Tay, F. R. AU - Pashley, D. H. AU - Breschi, L. PY - 2015 DA - 2015// TI - Role of dentin MMPs in caries progression and bond stability JO - J Dent Res VL - 94 UR - https://doi.org/10.1177/0022034514562833 DO - 10.1177/0022034514562833 ID - Mazzoni2015 ER - TY - JOUR AU - Frenkel, E. S. AU - Ribbeck, K. PY - 2015 DA - 2015// TI - Salivary mucins protect surfaces from colonization by cariogenic bacteria JO - Appl Environ Microbiol VL - 81 UR - https://doi.org/10.1128/AEM.02573-14 DO - 10.1128/AEM.02573-14 ID - Frenkel2015 ER - TY - JOUR AU - Siqueira, W. L. AU - Zhang, W. AU - Helmerhorst, E. J. AU - Gygi, S. P. AU - Oppenheim, F. G. PY - 2007 DA - 2007// TI - Identification of protein components in in vivo human acquired enamel pellicle using LC-ESI-MS/MS JO - J Proteome Res VL - 6 UR - https://doi.org/10.1021/pr060580k DO - 10.1021/pr060580k ID - Siqueira2007 ER -