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Table 3 Follow-up of moderate (4–6 mm) and deep pockets (≥ 7 mm) detected at baseline and pocket closure at 3- and 12- months follow up

From: Clinical effects of probiotic or azithromycin as an adjunct to scaling and root planning in the treatment of stage III periodontitis: a pilot randomized controlled clinical trial

  3 months 12 months
Follow-up of moderate pockets detected at baseline (%)   
PPD ≤ 3 mm   
 Probiotic group (n = 16) 68.5 ± 16.4 80.3 ± 18.3
 Antibiotic group (n = 16) 74.0 ± 13.7 77.8 ± 18.9
 Placebo group (n = 15) 77.0 ± 14.7 77.2 ± 14.5
 p value (inter-group) 0.2877 0.6950
PPD 4–6 mm   
 Probiotic group (n = 16) 30.3 ± 15.9 18.8 ± 17.6
 Antibiotic group (n = 16) 25.6 ± 13.0 20.9 ± 17.1
 Placebo group (n = 15) 21.5 ± 13.1 21.5 ± 13.4
 p value (inter-group) 0.2391 0.7886
PPD ≥ 7 mm   
 Probiotic group (n = 16) 1.2 ± 2.0 0.9 ± 2.3
 Antibiotic group (n = 16) 0.4 ± 1.4 1.3 ± 2.6
 Placebo group (n = 15) 1.5 ± 3.8 1.3 ± 3.8
 p value (inter-group) 0.2861 0.8539
Follow-up of deep pockets detected at baseline (%)   
PPD ≤ 3 mm   
 Probiotic group (n = 16) 16.5 ± 28.5 42.4 ± 41.3
 Antibiotic group (n = 16) 33.0 ± 39.9 41.7 ± 43.9
 Placebo group (n = 15) 43.3 ± 38.7 38.8 ± 31.5
 p value (inter-group) 0.2087 0.9798
PPD 4–6 mm   
 Probiotic group (n = 16) 73.4 ± 30.9 47.0 ± 43.6
 Antibiotic group (n = 16) 50.2 ± 37.3 50.0 ± 41.6
 Placebo group (n = 15) 38.1 ± 28.1 45.9 ± 28.6
 p value (inter-group) 0.1019 0.9715
PPD ≥ 7 mm   
 Probiotic group (n = 16) 10.1 ± 17.7 10.6 ± 18.2
 Antibiotic group (n = 16) 16.8 ± 21.1 8.3 ± 18.0
 Placebo group (n = 15) 18.6 ± 26.6 15.3 ± 16.3
 p value (inter-group) 0.6924 0.3030
Pocket closure (%)   
 Probiotic group (n = 16) 65.3 ± 17.9 78.1 ± 20.0
 Antibiotic group (n = 16) 71.9 ± 14.4 76.7 ± 19.7
 Placebo group (n = 15) 73.3 ± 18.1 74.4 ± 16.8
 p value (inter-group) 0.3790 0.6660
  1. Data presented as mean ± SD. PPD probing pocket depth
  2. Inter-group comparison by ANOVA and Kruskal Wallis test (p < 0.05)