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Table 3 Follow-up of moderate (4–6 mm) and deep pockets (≥ 7 mm) detected at baseline and pocket closure at 3- and 12- months follow up

From: Clinical effects of probiotic or azithromycin as an adjunct to scaling and root planning in the treatment of stage III periodontitis: a pilot randomized controlled clinical trial

 

3 months

12 months

Follow-up of moderate pockets detected at baseline (%)

  

PPD ≤ 3 mm

  

 Probiotic group (n = 16)

68.5 ± 16.4

80.3 ± 18.3

 Antibiotic group (n = 16)

74.0 ± 13.7

77.8 ± 18.9

 Placebo group (n = 15)

77.0 ± 14.7

77.2 ± 14.5

 p value (inter-group)

0.2877

0.6950

PPD 4–6 mm

  

 Probiotic group (n = 16)

30.3 ± 15.9

18.8 ± 17.6

 Antibiotic group (n = 16)

25.6 ± 13.0

20.9 ± 17.1

 Placebo group (n = 15)

21.5 ± 13.1

21.5 ± 13.4

 p value (inter-group)

0.2391

0.7886

PPD ≥ 7 mm

  

 Probiotic group (n = 16)

1.2 ± 2.0

0.9 ± 2.3

 Antibiotic group (n = 16)

0.4 ± 1.4

1.3 ± 2.6

 Placebo group (n = 15)

1.5 ± 3.8

1.3 ± 3.8

 p value (inter-group)

0.2861

0.8539

Follow-up of deep pockets detected at baseline (%)

  

PPD ≤ 3 mm

  

 Probiotic group (n = 16)

16.5 ± 28.5

42.4 ± 41.3

 Antibiotic group (n = 16)

33.0 ± 39.9

41.7 ± 43.9

 Placebo group (n = 15)

43.3 ± 38.7

38.8 ± 31.5

 p value (inter-group)

0.2087

0.9798

PPD 4–6 mm

  

 Probiotic group (n = 16)

73.4 ± 30.9

47.0 ± 43.6

 Antibiotic group (n = 16)

50.2 ± 37.3

50.0 ± 41.6

 Placebo group (n = 15)

38.1 ± 28.1

45.9 ± 28.6

 p value (inter-group)

0.1019

0.9715

PPD ≥ 7 mm

  

 Probiotic group (n = 16)

10.1 ± 17.7

10.6 ± 18.2

 Antibiotic group (n = 16)

16.8 ± 21.1

8.3 ± 18.0

 Placebo group (n = 15)

18.6 ± 26.6

15.3 ± 16.3

 p value (inter-group)

0.6924

0.3030

Pocket closure (%)

  

 Probiotic group (n = 16)

65.3 ± 17.9

78.1 ± 20.0

 Antibiotic group (n = 16)

71.9 ± 14.4

76.7 ± 19.7

 Placebo group (n = 15)

73.3 ± 18.1

74.4 ± 16.8

 p value (inter-group)

0.3790

0.6660

  1. Data presented as mean ± SD. PPD probing pocket depth
  2. Inter-group comparison by ANOVA and Kruskal Wallis test (p < 0.05)