Table 1 Description of the study sample for both periods of time

Age (median, IQR) [years]

3; 2–4

3; 2–4

3; 2–4

0.031^†*

% female (n)

41.6 (269)

43.1 (144)

39.0 (138)

0.24^#

% migration background (n)

30.8 (201)

27.5 (92)

32.5 (115)

0.06^#

% general disease (n)

8.7 (57)

4.5 (15)

13.2 (42)

< 0.001^#*

BMI (median, IQR) [kg/m²]

n = 556

15.6; 14.6–17.0

n = 276

15.9; 14.6–17.2

n = 280

15.4; 14.5–16.9

Nutritional status

n = 555

n = 276

n = 279

0.56^#

 % underweight (n)

17.3 (96)

17.4 (48)

17.2 (48)

 % normal weight (n)

67.9 (377)

66.3 (183)

69.5 (194)

 % overweight (n)

14.8 (82)

16.3 (45)

13.3 (37)

dmf-t (median, IQR)

n = 478

10.0; 7.0–13.0

n = 224

10.0; 7.0–13.0

n = 254

10.0; 7.0–13.0

0.21^†

dmf-s (median, IQR)

n = 401

28.0; 19.0–43.5

n = 162

29.0; 20.8–44.0

n = 239

28.0; 18.0–43.0

0.30^†

Reason for treatment

0.03^#*

 % age (n)

61.8 (403)

66.2 (221)

57.2 (182)

 % no compliance (n)

19.8 (129)

16.8 (56)

23.0 (73)

 % treatment need (n)

18.3 (119)

17.1 (57)

19.5 (62)

 % risk of bleeding (n)

0.2 (1)

0 (0)

0.3 (1)