Parameter | Study group (N = 67) | Control group (N = 40) | p | |
---|---|---|---|---|
Anthropometry data | ||||
Age [years] | 54.22 (± 7.05) | 52 (± 8.43) | NS | |
Weight [kg] | 84.17 (± 15.43) | 72.47 (± 16.84) | NS | |
Height [cm] | 171.90 (± 8.22) | 169.71(± 9.59) | NS | |
BMI [kg/m2] | 28.15 (± 4.21) | 25.04 (± 5.21) | < 0.05 | |
Medical history | ||||
Hypertension [N(%)] | 45 (68%) | 2 (5%) | < 0.05 | |
Diabetes [N(%)] | 16 (24%) | 2 (5%) | < 0.05 | |
Dyslipidemia [N(%)] | 36 (53%) | 5 (12.5%) | < 0.05 | |
Smoking [N(%)] | 48 (72%) | 26 (65%) | NS | |
Previous myocardial infarction [N(%)] | 11 (17%) | 0 (0%) | < 0.05 | |
Peripheral artery disease [N(%)] | 2 (3%) | 0 (0%) | < 0.05 | |
Family history of cardiovascular disease [N(%)] | 12 (18%) | 5 (12.5%) | < 0.05 | |
Pressure value | ||||
Systolic blood pressure [mmHg] | 139.42 (± 28.35) | 138.75 (± 31.43) | NS | |
Diastolic blood pressure [mmHg] | 85.23 (± 15.6) | 84.22(± 16.43) | NS | |
Medication | ||||
Aspirin [N(%)] | 64 (96%) | 5 (12.5%) | < 0.05 | |
P2Y12 inhibitors [N(%)] | 64 (96%) | 0 (0%) | < 0.05 | |
Beta-blockers [N(%)] | 60 (90%) | 10 (25%) | < 0.05 | |
ACE-inhibitors [N(%)] | 49 (73%) | 4 (10%) | < 0.05 | |
Sartans [N(%)] | 13 (20%) | 0 (0%) | < 0.05 | |
Statins [N(%)] | 67 (100%) | 0 (0%) | < 0.05 | |
Fibrats [N(%)] | 0 (0%) | 0 (0%) | < 0.05 | |
Diuretics [N(%)] | 5 (7%) | 0 (0%) | < 0.05 | |
Nonsteroidal anti-inflammatory drugs [N(%)] | 0 (0%) | 0 (0%) | NS | |
Laboratory data | ||||
Inflammation parameters | ||||
hsCRP [mg/l] | 8.34 (± 18.72) | 1.23 (± 3.55) | < 0.05 | |
ESR [mm/h] | 28.69 (± 17.62) | 5.01 (± 3.42) | < 0.05 | |
Leukocytes [109/l] | 10.82 (± 3.87) | 6.48 (± 2.57) | < 0.05 | |
Neutrophiles [%] | 57.3 (± 5.7) | 53.2 (± 3.8) | NS | |
Lymphocytes [%] | 10.5 (± 4.0) | 12.4 (± 4.5) | NS | |
N/L ratio [n] | 4.12 (± 2.85) | 4.29 (± 2.01) | < 0.05 | |
Fibrinogen [g/l] | 4.62 (± 1.09) | 4.11 (± 1.11) | < 0.05 | |
Parameters of myocardial injury | ||||
TnI [ng/ml] | 31.24 (± 20.40) | 0.19 (± 0.09) | < 0.05 | |
CK-MB [U/l] | 126.53 (± 111.06) | 9.34 (± 3.22) | < 0.05 | |
Parameters of heart failure | ||||
BNP [pg/ml] | 145.43 (± 181.31) | 64.96 (± 22.62) | < 0.05 | |
Lipidogram | ||||
Total cholesterol [mg/dl] | 208.96 (± 50.72) | 189.36 (± 23.94) | < 0.05 | |
LDL-cholesterol [mg/dl] | 131.01 (± 45.56) | 111.83 (± 34.65) | < 0.05 | |
HDL-cholesterol [mg/dl] | 46.8 (± 13.34) | 47.89 (± 11.83) | NS | |
TG [mg/dl] | 171.36 (± 107.88) | 145.52 (± 45.31) | < 0.05 | |
Glucose [mg/dl] | 145.01 (± 65.66) | 98.11 (± 22.34) | < 0.05 | |
Blood morphology | ||||
Hemoglobin [g/dl] | 13.2 (± 1.14) | 13.6 (± 1.23) | NS | |
Hematocrit [%] | 43.3 (± 4.9) | 44.1 (± 4.6) | NS | |
Red cells count [1012/l] | 4.11 (± 0.31) | 4.32 (± 0.29) | NS | |
Platelets count [109/l] | 176.6 (± 70.1) | 173.5 (± 54.50) | NS | |
Other | ||||
Creatinine [mg/dl] | 0.85 (± 0.21) | 0.82 (± 19.2) | NS | |
GFR [ml/min/1.73 m2] | 62.4 (± 14.7) | 78.9 (± 12.4) | < 0.05 | |
TSH [mU/l] | 1.78 (± 3.57) | 1.65 (± 2.91) | NS | |
HbA1C [%] | 6.03 (± 1.14) | 5.51 (± 0.52) | < 0.05 | |
Coronarography results | ||||
Right coronary artery [N(%)] | 32 (48%) | NA | ||
Left main coronary artery [N(%)] | 2 (3%) | NA | ||
Left anterior descending artery [N(%)] | 50 (75%) | NA | ||
Circumflex artery [N(%)] | 34 (51%) | NA | ||
Echocardiography data | ||||
Left ventricle end diastolic diameter [mm] | 52.1 (± 4.5) | 51.1 (± 4.9) | NS | |
Left ventricle end systolic diameter [mm] | 10.8 (± 1.12) | 10.42 (± 1.09) | NS | |
Left ventricle ejection fraction [%] | 54.58 (± 6.95) | 65.09 (± 6.32) | < 0.001 | |
Left atrium maximal diameter [mm] | 39.5 (± 4.1) | 37.6 (± 3.9) | NS | |
Right ventricle end diastolic diameter [mm] | 2.84 (± 1.09) | 2.67 (± 1.21) | NS | |
Parameters from dental examination | ||||
Number of preserved teeth [n] | 17.28 (± 6.42) | 23.53 (± 5.46) | < 0.001 | |
API [%] | 77.68 (± 26.24) | 39.44 (± 27.93) | < 0.001 | |
BoP [%] | 42.99 (± 23.88) | 44.42 (± 26.36) | NS | |
PD [mm] | 2.64 (± 0.99) | 2.02 ± (± 0.74) | < 0.001 | |
CAL [mm] | 3.15 (± 1.98) | 1.53 (± 1.81) | < 0.001 |