Skip to main content

Table 2 Comparisons of perioperative red blood cell related findings between the two groups

From: Preemptive intravenous iron therapy versus autologous whole blood therapy for early postoperative hemoglobin level in patients undergoing bimaxillary orthognathic surgery: a prospective randomized noninferiority trial

Group

Intravenous iron

Autologous whole blood

p

n

32

32

Four weeks before surgery (baseline)

 Hemoglobin (g/dL)

14.5 ± 1.4

14.3 ± 1.4

0.529

 Hematocrit (%)

42.8 ± 3.8

42.5 ± 3.6

0.79

 RBC count (× 1012/L)

4.8 ± 0.4

4.7 ± 0.4

0.491

Red cell index

 MCV (fL)

89.2 ± 3.5

89.3 ± 2.3

0.831

 MCH (pg)

30.1 ± 1.3

30.1 ± 1.0

0.991

 MCHC (%)

33.9 ± 0.9

33.5 ± 0.7

0.09

 Iron (μg/dL)

128.9 ± 48.6

113.3 ± 42.4

0.176

 Ferritin (ng/mL)

105.7 ± 92.9

107.5 ± 77.7

0.932

Immediately before surgery

 Hemoglobin (g/dL)

13.5 ± 1.4***

12.0 ± 2.0***

 < 0.001

 Hematocrit (%)

40.2 ± 2.7***

35.5 ± 5.5***

 < 0.001

 RBC count (× 1012/L)

4.5 ± 0.4***

4.0 ± 0.6***

 < 0.001

Red cell index

 MCV (fL)

89.5 ± 3.4

89.1 ± 3.7

0.617

 MCH (pg)

30.1 ± 1.3

30.0 ± 1.4

0.631

 MCHC (%)

33.8 ± 0.8

33.6 ± 0.7

0.401

 Iron (μg/dL)

98.6 ± 33.0***

62.2 ± 40.9***

 < 0.001

 Ferritin (ng/mL)

271.2 ± 156.4**

66.3 ± 111.6

 < 0.001

Postoperative day 1

 Hemoglobin (g/dL)

10.1 ± 1.9***

10.1 ± 1.8***

0.849

 Hematocrit (%)

30.1 ± 5.5***

29.7 ± 4.9***

0.765

 RBC count (× 1012/L)

3.4 ± 0.6***

3.4 ± 0.6***

0.697

Red cell index

 MCV (fL)

89.0 ± 1.7

89.4 ± 3.3

0.542

 MCH (pg)

30.0 ± 0.7

30.0 ± 1.2

0.829

 MCHC (%)

33.7 ± 0.7

33.7 ± 0.8

0.961

 Iron (μg/dL)

40.6 ± 29.8***

22.7 ± 12.1***

0.002

 Ferritin (ng/mL)

265.2 ± 161.1***

102.3 ± 96.2

 < 0.001

Postoperative day 2

 Hemoglobin (g/dL)

9.1 ± 1.6***

9.9 ± 1.4***

0.035

 Hematocrit (%)

26.9 ± 4.9***

29.4 ± 4.3***

0.036

 RBC count (× 1012/L)

3.0 ± 0.6***

3.3 ± 0.5***

0.022

Red cell index

 MCV (fL)

89.8 ± 2.5

89.9 ± 3.5

0.823

 MCH (pg)

30.4 ± 1.0

29.9 ± 1.3

0.081

 MCHC (%)

33.9 ± 0.5

33.7 ± 0.7

0.433

 Iron (μg/dL)

63.0 ± 26.4***

41.4 ± 22.9***

0.001

 Ferritin (ng/mL)

281.8 ± 150.3***

107.3 ± 93.5

 < 0.001

  1. Values are expressed as mean ± SD and number (proportion)
  2. RBC red blood cell, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, HCHC mean corpuscular hemoglobin concentration
  3. *p < 0.05 based on the level at 4 weeks before surgery (baseline)
  4. **p < 0.01 based on the level at 4 weeks before surgery (baseline)
  5. ***p < 0.001 based on the level at 4 weeks before surgery (baseline)