Group
|
Intravenous iron
|
Autologous whole blood
|
p
|
---|
n
|
32
|
32
|
---|
Four weeks before surgery (baseline)
|
Hemoglobin (g/dL)
|
14.5 ± 1.4
|
14.3 ± 1.4
|
0.529
|
Hematocrit (%)
|
42.8 ± 3.8
|
42.5 ± 3.6
|
0.79
|
RBC count (× 1012/L)
|
4.8 ± 0.4
|
4.7 ± 0.4
|
0.491
|
Red cell index
|
MCV (fL)
|
89.2 ± 3.5
|
89.3 ± 2.3
|
0.831
|
MCH (pg)
|
30.1 ± 1.3
|
30.1 ± 1.0
|
0.991
|
MCHC (%)
|
33.9 ± 0.9
|
33.5 ± 0.7
|
0.09
|
Iron (μg/dL)
|
128.9 ± 48.6
|
113.3 ± 42.4
|
0.176
|
Ferritin (ng/mL)
|
105.7 ± 92.9
|
107.5 ± 77.7
|
0.932
|
Immediately before surgery
|
Hemoglobin (g/dL)
|
13.5 ± 1.4***
|
12.0 ± 2.0***
|
< 0.001
|
Hematocrit (%)
|
40.2 ± 2.7***
|
35.5 ± 5.5***
|
< 0.001
|
RBC count (× 1012/L)
|
4.5 ± 0.4***
|
4.0 ± 0.6***
|
< 0.001
|
Red cell index
|
MCV (fL)
|
89.5 ± 3.4
|
89.1 ± 3.7
|
0.617
|
MCH (pg)
|
30.1 ± 1.3
|
30.0 ± 1.4
|
0.631
|
MCHC (%)
|
33.8 ± 0.8
|
33.6 ± 0.7
|
0.401
|
Iron (μg/dL)
|
98.6 ± 33.0***
|
62.2 ± 40.9***
|
< 0.001
|
Ferritin (ng/mL)
|
271.2 ± 156.4**
|
66.3 ± 111.6
|
< 0.001
|
Postoperative day 1
|
Hemoglobin (g/dL)
|
10.1 ± 1.9***
|
10.1 ± 1.8***
|
0.849
|
Hematocrit (%)
|
30.1 ± 5.5***
|
29.7 ± 4.9***
|
0.765
|
RBC count (× 1012/L)
|
3.4 ± 0.6***
|
3.4 ± 0.6***
|
0.697
|
Red cell index
|
MCV (fL)
|
89.0 ± 1.7
|
89.4 ± 3.3
|
0.542
|
MCH (pg)
|
30.0 ± 0.7
|
30.0 ± 1.2
|
0.829
|
MCHC (%)
|
33.7 ± 0.7
|
33.7 ± 0.8
|
0.961
|
Iron (μg/dL)
|
40.6 ± 29.8***
|
22.7 ± 12.1***
|
0.002
|
Ferritin (ng/mL)
|
265.2 ± 161.1***
|
102.3 ± 96.2
|
< 0.001
|
Postoperative day 2
|
Hemoglobin (g/dL)
|
9.1 ± 1.6***
|
9.9 ± 1.4***
|
0.035
|
Hematocrit (%)
|
26.9 ± 4.9***
|
29.4 ± 4.3***
|
0.036
|
RBC count (× 1012/L)
|
3.0 ± 0.6***
|
3.3 ± 0.5***
|
0.022
|
Red cell index
|
MCV (fL)
|
89.8 ± 2.5
|
89.9 ± 3.5
|
0.823
|
MCH (pg)
|
30.4 ± 1.0
|
29.9 ± 1.3
|
0.081
|
MCHC (%)
|
33.9 ± 0.5
|
33.7 ± 0.7
|
0.433
|
Iron (μg/dL)
|
63.0 ± 26.4***
|
41.4 ± 22.9***
|
0.001
|
Ferritin (ng/mL)
|
281.8 ± 150.3***
|
107.3 ± 93.5
|
< 0.001
|
- Values are expressed as mean ± SD and number (proportion)
- RBC red blood cell, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, HCHC mean corpuscular hemoglobin concentration
- *p < 0.05 based on the level at 4 weeks before surgery (baseline)
- **p < 0.01 based on the level at 4 weeks before surgery (baseline)
- ***p < 0.001 based on the level at 4 weeks before surgery (baseline)