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Fig. 5 | BMC Oral Health

Fig. 5

From: Differential expression of matrix metalloproteinases and miRNAs in the metastasis of oral squamous cell carcinoma

Fig. 5

Validation of the important MMP-related DEGs and DE-miRNAs. a The expression levels of MMP7 and MMP13 were significantly upregulated in oral cancer compared with normal samples according to the data mining of published profiles in Oncomine. b qRT-PCR confirmed that the expression levels of MMP7 and MMP13 were significantly increased in the metastatic tumour samples, while MMP10 was not; c qRT-PCR confirmed that the expression levels of miR-7109-5p and miR-34b were significantly downregulated in the metastatic OSCC samples compared with the nonmetastatic tumour samples. The samples were collected from another eight nonmetastatic OSCC patients and seven metastatic OSCC patients

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