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Table 2 Risk of bias assessment

From: Adjunctive subgingival application of Chlorhexidine gel in nonsurgical periodontal treatment for chronic periodontitis: a systematic review and meta-analysis

Author (year)Random sequence generationAllocation concealmentBlinding of participants and personnelBlinding of outcome assessmentIncomplete outcome dataSelective reportingOther biasRisk of bias 
Faramarzi M et al. (2017) [26]?low 
Phogat M et al. (2014) [27]??Xx??highexclusion
Jain M et al. (2013) [28]??Xx?highexclusion
Chitsazi MT et al. (2013) [29]?low 
Chauhan AS et al. (2013) [30]??Xx?highexclusion
Verma A et al. (2012) [32]??Xx??highexclusion
Matesanz P et al. (2013) [31]low 
Kranti K et al. (2010) [33]??unclear 
Paolantonio M. (2009) [34]?Xhigh 
Gupta R et al. (2008) [35]??Xx??highexclusion
Fonseca DC 2015 [17]?low 
santos VR 2013 [18]?low 
Quirynen M 2006 [2]x?high 
Swierkot K 2009 [19]?xhigh 
unsal E 1994 [11]??xxhighexclusion
lecic J 2016 [10]?low 
Oosterwaal PJM 1991 [12]??unclear 
  1. : low risk of bias;?: unclear risk of bias; x: high risk of bias;
  2. Exclusion: when a trial did not meet all four criteria for randomization and blinding methods, it was excluded from quantitative analysis, as its low quality and high bias may have subverted the validity of the results and conclusions