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Table 1 Characteristics of included studies in this current meta-analysis

From: Non-significant association between − 330 T/G polymorphism in interleukin-2 gene and chronic periodontitis: findings from a meta-analysis

First Author and Reference

Year of Publication

Country

Ethnicity

Sample Size (Cc/Co)

Majumder [24]

2019

India

Asian

157/200

Li [20]

2012

China

Asian

122/532

Reichert [25]

2009

Germany

Caucasian

58/69

Scarel-Caminaga [19]

2002

Brazil

Mixed

69/44

Vahabi [26]

2017

Iran

Caucasian

99/75

First Author and Reference

Year of Publication

Genotypic Frequency (Cc- GG,TG,TT/Co- GG,TG,TT)

Age (Cc/Co)

Score and HWE respect (X2, Pvalue)

Majumder [24]

2019

72,62,23/90,79,31

41.59 ± 11.12/38.41 ± 9.48

14/Yes (X2 < 3.84, P > 0.05)

Li [20]

2012

40,14,68/43,111,378

38.00–69.00

14/No (X2 > 3.84, P < 0.05)

Reichert [25]

2009

8,15,35/16,51,64

49.1 ± 9.6/46.7 ± 10.7

14/No (NI)

Scarel-Caminaga [19]

2002

4,29,36/2,16,26

36.9 ± 11.2(I)-43.6 ± 14.4(II)/43.2 ± 14.0

14/NI

Vahabi [26]

2017

0,0,99/0,0,75

40.28 ± 12.73/31.67 ± 12.00

12/NI

  1. Cc Case patients, Co Healthy Controls, I and II Both studies performed by Scarel-Caminaga [18], HWE Hardy Weinberg Equilibrium with based on X2 test value and Pvalue > 0.05, HWE Evaluated in case and control groups combined, NI Not informed