Table 1 Demographic and clinical characteristics of study patients, n = 400
Period 1 (01–2009–09–2015) | Period 2 (10–2015–09–2018) | |||||
|---|---|---|---|---|---|---|
Variable | Department A (n = 118) | Department B (n = 118) | p value | Department A (n = 82) | Department B (n = 82) | p value |
Gender | 0.232 | 0.773 | ||||
Male | 106(89.8) | 111(94.1) | 75(91.5) | 76(92.7) | ||
Female | 12(10.2) | 7(5.9) | 7(8.5) | 6(7.3) | ||
Age (Mean ± SD) | 56.4 ± 11.2 | 52.7 ± 10.3 | 0.008 | 55.5 ± 10.0 | 55.3 ± 12.0 | 0.916 |
cN classification | 0.091 | 0.073 | ||||
N0 | 57(48.3) | 62(52.5) | 45(55.6) | 60(73.2) | ||
N1 | 20(16.9) | 9(7.6) | 10(12.3) | 8(9.8) | ||
N2 | 41(34.7) | 47(39.8) | 26(31.7) | 14(17.1) | ||
N3 | 0(0.0) | 0(0.0) | 1(0.9) | 0(0.0) | ||
cT classification | 0.152 | 0.148 | ||||
T1 | 26(22.0) | 19(16.1) | 16(19.8) | 21(25.6) | ||
T2 | 46(39.0) | 42(35.6) | 28(34.1) | 22(26.8) | ||
T3 | 7(5.9) | 3(2.5) | 12(14.8) | 5(6.1) | ||
T4 | 39(33.1) | 54(45.8) | 26(32.1) | 34(41.5) | ||
Differentiation | 0.085 | 0.682 | ||||
Well | 17(14.4) | 27(22.9) | 14(17.1) | 14(17.1) | ||
Moderately | 91(77.1) | 87(73.7) | 60(73.2) | 63(76.8) | ||
Poorly | 10(8.5) | 4(3.4) | 8(9.8) | 5(6.1) | ||
Tumor subsite | < 0.001 | 0.002 | ||||
Tongue | 63(53.4) | 22(18.6) | 36(43.9) | 18(22.0) | ||
Buccal | 40(33.9) | 55(46.6) | 32(39) | 33(40.2) | ||
Other sites | 15(12.7) | 41(34.7) | 14(17.1) | 31(37.8) | ||
Margin | 0.651 | 0.096 | ||||
Negative | 116(98.3) | 115(97.5) | 77(93.9) | 81(98.7) | ||
Positive | 2(1.7) | 3(2.5) | 5(6.1) | 1(1.2) | ||
Adjuvant treatment | 0.002 | 0.064 | ||||
Nil | 56(47.5) | 54(45.8) | 35(42.7) | 50(61.0) | ||
RT | 47(39.8) | 29(24.6) | 36(43.9) | 23(28.0) | ||
CT | 2(1.7) | 14(11.9) | 0(0.0) | 0(0.0) | ||
RT + CT | 13(11.0) | 21(17.8) | 11(13.4) | 9(11.0) | ||