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Table 1 Association between peritumoral lymphatic vessel density and clinicopathologic variables in oral squamous cell carcinomas. A.C.Camargo Cancer Hospital. São Paulo, Brazil

From: Association of lymph vessel density with occult lymph node metastasis and prognosis in oral squamous cell carcinoma

Variable Peritumoral lymphatic vessel density
Sequential analysis p value Hot spot evaluation p value
Low High Low High
Gender       
 Male
 Female
35 (77.8%)
10 (22.2%)
33 (78.6%)
09 (21.4%)
0.929 32 (76.2%)
10 (23.8%)
36 (80.0%)
09 (20.0%)
0.667
Ethnic group       
 White
 Not white
40 (88.9%)
05 (11.1%)
40 (95.2%)
02 (4.8%)
0.435 37 (88.1%)
05 (11.9%)
43 (95.6%)
02 (4.4%)
0.255
Age       
 ≤ 59 years
 > 59 years
22 (48.9%)
23 (51.1%)
23 (54.8%)
19 (45.2%)
0.584 21 (50.0%)
21 (50.0%)
24 (53.3%)
21 (46.7%)
0.756
Tobacco#       
 No
 Yes
05 (11.9%)
37 (88.1%)
04 (10.3%)
35 (89.7%)
1.000 05 (13.2%)
33 (86.8%)
04 (9.3%)
39 (90.75)
0.728
Alcohol#       
 No
 Yes
09 (21.4%)
33 (78.6%)
06 (15.4%)
33 (84.6%)
0.484 06 (15.8%)
32 (84.2%)
09 (20.9%)
34 (79.1%)
0.552
Tumor site       
 Tongue
 Floor of mouth
30 (66.7%)
15 (33.3%)
30 (71.4%)
12 (28.6%)
0.631 31 (73.8%)
11 (26.2%)
29 (64.4%)
16 (35.6%)
0.345
T stage       
 T1
 T2
12 (26.7%)
33 (73.3%)
16 (38.1%)
26 (61.9%)
0.254 12 (28.6%)
30 (71.4%)
16 (35.6%)
29 (64.4%)
0.486
Local recurrence       
 No
 Yes
34 (75.6%)
11 (24.4%)
38 (90.5%)
04 (9.5%)
0.066 34 (81.0%)
08 (19.0%)
38 (84.4%)
07 (15.6%)
0.667
Regional recurrence       
 No
 Yes
38 (84.4)
07 (15.6)
35 (83.3%)
07 (16.7%)
0.888 36 (85.7)
06 (14.3%)
37 (82.2%)
08 (17.8%)
0.658
Lymphatic embolization       
 No
 Yes
30 (66.7%)
15 (33.3%)
32 (76.2%)
10 (23.8%)
0.327 28 (66.7%)
14 (33.3%)
34 (75.6%)
11 (24.4%)
0.360
Blood embolization       
 No
 Yes
39 (86.7%)
06 (13.3%)
36 (85.7%)
06 (14.3%)
0.898 37 (88.1%)
05 (11.9%)
38 (84.4%)
07 (15.6%)
0.622
Perineural infiltration       
 No
 Yes
18 (40.0%)
27 (60.0%)
25 (59,5%)
17 (40.5%)
0.069 16 (38.1%)
26 (61.9%)
27 (60.0%)
18 (40.0%)
0.041
Muscular infiltration       
 No
 Yes
06 (13.3%)
39 (86.7%)
10 (23.8%)
32 (76.2%)
0.208 05 (11.9%)
37 (88.1%)
11 (24.4%)
34 (75.6%)
0.131
Salivary gland infiltration       
 No
 Yes
25 (55.6%)
20 (44.4%)
33 (78.6%)
09 (21.4%)
0.230 27 (64.3%)
15 (35.7%)
31 (68.9%)
14 (31.1%)
0.649
Lymph-nodal status#       
 pN0
 pN + 
30 (81.1%)
07 (18.9%)
20 (74.1%)
07 (25.9%)
0.503 26 (76.5%)
08 (23.5%)
24 (80.0%)
06 (20.0%)
0.733
Malignancy grading       
 More differentiated
 Less differentiated
35 (77.8%)
10 (22.2%)
34 (81.0%)
08 (19.0%)
0.715 32 (76.2%)
10 (23.8%)
37 (82.2%)
08 (17.8%)
0.488
  1. # Excluding patients with lost records