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Table 2 Association between intratumoral lymphatic vessel density and clinicopathologic variables in oral squamous cell carcinomas. A.C.Camargo Cancer Hospital. São Paulo, Brazil

From: Association of lymph vessel density with occult lymph node metastasis and prognosis in oral squamous cell carcinoma

Variable Intratumoral lymphatic vessel density
Sequential analysis p value Hot spot evaluation p value
Low High Low High
Gender       
 Male
 Female
43 (86.0%)
07 (14.0%)
25 (67.6%)
12 (32.4%)
0.040 38 (82.6%)
08 (17.4%)
30 (73.2%)
11 (26.8%)
0.288
Ethnic group       
 White
 Not white
47 (94.0%)
03 (6.0%)
33 (89.2%)
04 (10.8%)
0.452 44 (95.7%)
02 (4.3%)
36 (87.8%)
05 (12.2%)
0.247
Age       
 ≤ 59 years
 > 59 years
28 (56.0%)
22 (44.0%)
17 (45.9%)
20 (54.1%)
0.354 25 (54.3%)
21 (45.7%)
20 (48.8%)
21 (51.2%)
0.604
Tobacco#       
 No
 Yes
04 (8.5%)
43 (91.5%)
05 (14.7%)
29 (85.3%)
0.481 05 (11.6%)
38 (88.450
04 (10.5%)
34 (89.5%)
1.000
 Alcohol#       
 No
 Yes
08 (17.0%)
39 (83.0%)
07 (20.6%)
27 (79.4%)
0.683 08 (18.6%)
35 (81.4%)
07 (18.4%)
31 (81.6%)
0.983
Tumor site       
 Tongue
 Floor of mouth
34 (68.0%)
16 (32.0%)
26 (70.3%)
11 (29.7%)
0.821 31 (67.4%)
15 (32.6%)
29 (70.7%)
12 (29.3%)
0.737
T stage       
 T1
 T2
19 (38.0%)
31 (62.0%)
09 (24.3%)
28 (75.7%)
0.177 18 (39.1%)
28 (60.9%)
10 (24.4%)
31 (75.6%)
0.142
Local recurrence       
 No
 Yes
41 (82.0%)
09 (18.0%)
31 (83.8%)
06 (16.2%)
0.828 37 (80.4%)
09 (19.6%)
35 (85.4%)
06 (14.6%)
0.543
Regional recurrence       
 No
 Yes
45 (90.0%)
05 (10.0%)
28 (75.7%)
09 (24.3%)
0.072 42 (91.3%)
04 (8.7%)
31 (75.6%)
10 (24.4%)
0.047
Lymphatic embolization       
 No
Yes
38 (76.0%)
12 (24.0%)
24 (64.9%)
13 (35.1%)
0.257 36 (78.3%)
10 (21.75)
26 (63.4%)
15 (36.6%)
0.127
Blood embolization       
 No
 Yes
43 (86.0%)
07 (14.0%)
32 (86.5%)
05 (13.5%)
0.948 39 (84.8%)
07 (15.2%)
36 (87.8%)
05 (12.2%)
0.683
Perineural infiltration       
 No
 Yes
26 (52.0%)
24 (48.0%)
17 (45.9%)
20 (54.1%)
0.577 25 (54.3%)
21 (45.7%)
18 (43.9%)
23 (56.1%)
0.331
Muscular infiltration       
 No
 Yes
11 (22.0%)
39 (780%)
05 (13.5%)
32 (86.5%)
0.312 10 (21.7%)
36 (78.3%)
06 (14.6%)
35 (85.4%)
0.393
Salivary gland infiltration       
 No
 Yes
34 (68.0%)
16 (32.0%)
24 (64.9%)
13 (35.1%)
0.759 33 (71.7%)
13 (28.3%)
25 (61.0%)
16 (39.0%)
0.288
Lymph-nodal status#       
 pN0
 pN + 
32 (84.2%)
06 (15.8%)
18 (69.2%)
08 (30.8%)
0.155 29 (82.9%)
06 (17.1%)
21 (72.4%)
08 (27.6%)
0.314
Malignancy grading       
 More differentiated
 Less differentiated
38 (76.0%)
12 (24.0%)
31 (83.8%)
06 (16.2%)
0.376 34 (73.9%)
12 (26.1%)
35 (85.4%)
06 (14.6%)
0.188
  1. #Excluding patients with lost records