From: Salivary Porphyromonas gingivalis predicts outcome in oral squamous cell carcinomas: a cohort study
Parameters | Â | Number (%) | Porphyromonas gingivalis | P value | |
---|---|---|---|---|---|
Low | High | ||||
Age (years) | 55.8 ± 12.7 | 95 (100) | 55.7 ± 12.6 | 56.5 ± 14.6 | 0.860 |
Gender | Male | 65 (68.4) | 57 | 8 | 0.999 |
Female | 30 (31.6) | 27 | 3 | Â | |
Systemic disease | No | 69 (72.6) | 61 | 8 | 0.999 |
Yes | 26 (27.4) | 23 | 3 | Â | |
Pathologic staging | pStage I + II | 69 (72.6) | 65 | 4 | 0.008 |
pStage III + IV | 26 (27.4) | 19 | 7 |  | |
Smoking | No | 45 (47.4) | 39 | 6 | 0.612 |
Yes | 50 (52.6) | 45 | 5 | Â | |
Alcohol consumption | No | 57 (60.0) | 50 | 7 | 0.999 |
Yes | 38 (40.0) | 34 | 4 | Â | |
Location | Buccal | 21 (24.2) | 21 | 2 | 0.447 |
Tongue | 52 (54.7) | 47 | 5 | Â | |
Gingiva | 11 (11.6) | 9 | 2 | Â | |
Floor of mouth | 5 (5.3) | 4 | 1 | Â | |
Hard palate | 4 (4.2) | 3 | 1 | Â | |
Differentiation grade | Well | 17 (19.1) | 16 | 1 | 0.735 |
Moderate | 65 (73.0) | 57 | 8 | Â | |
Poor | 7 (7.9) | 6 | 1 | Â | |
FimA genotypes | I + Ib | 20 (21.1) | 17 | 3 | 0.795* |
II | 30 (31.6) | 27 | 3 | Â | |
III | 4 (4.2) | 4 | 0 | Â | |
IV | 20 (21.1) | 16 | 4 | Â | |
V | 2 (2.1) | 2 | 0 | Â | |
I + Ib + II | 1 (1.1) | 1 | 0 |  | |
I + Ib + III | 2 (2.1) | 2 | 0 |  | |
I + Ib + IV | 1 (1.1) | 1 | 0 |  | |
I + Ib + V | 1 (1.1) | 1 | 0 |  | |
II + IV | 3 (3.2) | 3 | 0 |  | |
I + Ib + II + IV | 1 (1.1) | 1 | 0 |  | |
Untyped | 10 (10.5) | 9 | 1 | Â | |
Treatment†| Surgery | 64 (68.1) | 60 | 4 | – |
Surgery + RT or CRT** | 30 (31.9) | 23 | 7 |  | |
Outcome†| Recurrence | 24 (25.5) | 25 | 0 | 0.033 |
Disease-free | 70 (74.5) | 58 | 11 | Â | |
Disease-free time (months) | 23, 10 | 94 (98.9) | 22, 13.8 | 27, 8 | 0.029 |