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Table 1 Demographics and clinical characteristics of RA and control subjects

From: Subgingival microbiome of deep and shallow periodontal sitesĀ in patients with rheumatoid arthritis: a pilot study

Characteristic

Biologic-naĆÆve RA (nā€‰=ā€‰8)

Non-RA control (nā€‰=ā€‰10)

P-value*

Age, years, mean

55.1 (16.5)

53.2 (16.0)

0.81

Female, %

62.5%

70.0%

1.0

Race+, %

Ā Caucasian

Ā Non-Caucasian

Ā Ā African American

Ā Ā Hispanic

Ā Ā Indian

Ā Ā Unknown

50%

50%

25%

12.5%

12.5%

0%

30%

70%

10%

10%

0%

50%

0.63

BMI (kg/m2)

32.6

ā€“

Ā 

Diabetes mellitus

0%

ā€“

Ā 

Smoking history

Ā Current

12.5%

ā€“

Ā 

Ā Former

37.5%

ā€“

Ā 

Ā Never

50%

ā€“

Ā 

RA disease characteristics

Ā Remission, %

75%

ā€“

ā€“

Ā Autoantibody status

Ā Ā RF positive, %

75%

ā€“

ā€“

Ā Ā ACPA positive, %

75%

ā€“

ā€“

Ā ESR mm/h, mean

23.38 (17.73)

ā€“

ā€“

Ā CRP mg/L, mean

4.26 (1.64)

ā€“

ā€“

Ā RAPID3 score, mean

10.42 (5.71)

ā€“

ā€“

Ā Medication history

Ā Ā DMARDs, %

100%

ā€“

ā€“

Ā Ā Glucocorticoids, %

0%

ā€“

ā€“

Ā Ā Biologic agents

Ā Ā Ā TNF-inhibitor, %

0%

ā€“

ā€“

Ā Ā Ā Other, %

0%

ā€“

ā€“

Number of caries, mean

3 (3.85)

4.4 (7.07)

0.62

Probing depth, mean (mm)

Ā Shallow sites (PDā€‰ā‰¤ā€‰3 mm)

2.58

2.08

0.02

Ā Deep sites (PDā€‰ā‰„ā€‰4 mm) $

4.00

3.65

0.47

Global PD status

Ā Healthy, %

12.5%

0%

0.54

Ā Periodontitis stage I, %

37.5%

40%

Ā Periodontitis stage II, %

12.5%

40%

Ā Periodontitis stage III, %

37.5%

20%

  1. RF, rheumatoid factor; ACPA, anti-cyclic citrullinated protein antibody; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; RAPID3, routine assessment of patient index data 3; DMARD, disease modifying antirheumatic drug; TNF, tumor necrosis factor; PD, periodontal disease. Periodontitis stages are described elsewhere [8, 28]
  2. *Age and pocket depth were compared using Studentā€™s t-test. All other parameters were compared using Fisherā€™s Exact test. P-value in race was calculated with Caucasian vs. non-Caucasian data. Standard deviation is shown in parentheses
  3. +Race was self-reported
  4. $Probing depths were averaged measurements from the facial and/or lingual sites from which subgingival samples were collected