Table 4 Performance of salivary biomarker combinations to discriminate periodontitis patients from healthy subjects
From: Evaluation of salivary biomarkers for the diagnosis of periodontitis
| Â | Sensitivity (%) | Specificity (%) | AUC value | 95% CI |
|---|---|---|---|---|
IL-1β + MMP-8 | 87.1 | 80.0 | 0.883 | 0.793–0.972 |
IL-1β + Pg | 87.1 | 84.0 | 0.910 | 0.828–0.991 |
IL-1β + MMP-8 + Pg | 90.3 | 84.0 | 0.920 | 0.843–0.997 |
ICTP + MMP-8 | 83.9 | 76.0 | 0.850 | 0.746–0.955 |
ICTP + Pg | 83.9 | 80.0 | 0.881 | 0.794–0.969 |
IL-1β + ICTP | 87.1 | 80.0 | 0.917 | 0.840–0.995 |
IL-1β + ICTP + MMP-8 | 90.3 | 84.0 | 0.929 | 0.865–0.993 |
IL-1β + ICTP + Pg | 93.5 | 84.0 | 0.935 | 0.873–0.998 |
IL-1β + ICTP + MMP-8 + Pg | 93.5 | 84.0 | 0.946 | 0.892–0.999 |