Fig. 2
From: Specialized pro-resolving lipid mediators in endodontics: a narrative review
Specialized lipid mediator synthesis. SPMs are all derived from free PUFAs released at the onset of inflammation, including arachidonic acid and ω-3 fatty acids: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA). COX, cyclooxygenase; HETE, hydroxyeicosatetraenoic acid; LO, lipoxygenase; LT, leukotriene; LX, lipoxin; H(p)EPE, hydroxyeicosapentaenoic acid; MaR, maresin; PD protectin; Rv, resolvin