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Table 3 Post intervention changes in periodontal and glycemic variables at different follow-up visits

From: Clinical efficacy of scaling and root planing with and without metronidazole on glycemic control: three-arm randomized controlled trial

Variables v/s intervention

On 1-month follow-up

On 3-months follow-up

Periodontal

Mean difference ∆

p-value*

p-value**

Mean difference ∆

p-value*

p-value**

Mean BOP %

      

SRP + MET + OHI − DT + OHI

 − 8.16

0.010

0.018

 − 10.72

 < 0.001

0.001

SRP + OHI − DT + OHI

 − 7.27

0.037

 − 11.94

 

 < 0.001

SRP + MET + OHI − SRP + OHI

 − 0.89

1.000

1.22

 

1.000

Mean PPD (mm)

      

SRP + MET + OHI − DT + OHI

 − 0.72

 < 0.001

0.001

 − 1.13

 < 0.001

 < 0.001

SRP + OHI − DT + OHI

 − 0.48

0.031

 − 0.74

 

0.008

SRP + MET + OHI − SRP + OHI

 − 0.24

0.593

 − 0.39

 

0.357

Mean CAL (mm)

      

SRP + MET + OHI − DT + OHI

 − 0.50

0.028

0.098

 − 0.63

 < 0.001

0.032

SRP + OHI − DT + OHI

 − 0.57

0.040

 − 1.05

 

 < 0.001

SRP + MET + OHI − SRP + OHI

0.07

1.000

0.41

 

0.309

Glycemic

On 3-months follow-up

On 6-months follow-up

HbA1c (%)

      

SRP + MET + OHI − DT + OHI

 − 1.22

 < 0.002

0.004

 − 2.18

 < 0.001

 < 0.001

SRP + OHI − DT + OHI

 − 0.98

0.023

 − 1.84

 

 < 0.001

SRP + MET + OHI − SRP + OHI

 − 0.24

1.000

 − 0.34

 

1.000

FBG (mg/dL)

      

SRP + MET + OHI − DT + OHI

 − 33.32

 < 0.023

0.042

 − 51.82

 < 0.001

0.001

SRP + OHI − DT + OHI

 − 29.48

0.068

 − 41.51

 

0.007

SRP + MET + OHI − SRP + OHI

 − 3.84

1.000

 − 10.31

 

1.000

  1. SRP, scaling root planning; MET, metronidazole; DT, delayed treatment; OHI, oral hygiene instructions
  2. ∆Between groups mean difference
  3. *All Significant difference between three groups [p < 0.05] measured by One-way ANOVA have been made bold
  4. **All Significant difference at p < 0.05 calculated through post-hoc bonferroni test have been made bold