Skip to main content

Table 2 Amount of 14C-lidocaine in the palatal bone

From: Effect of epinephrine on the absorption of lidocaine following application to the oral mucosa in rats

  Lidocaine
Mean ± SD
Lidocaine with epinephrine
Mean ± SD
p value
Sample size 5 5  
Time (min)    
 0.5 1.8 ± 0.4 1.9 ± 0.5 0.738
 2 3.9 ± 0.6 4.3 ± 0.6 0.378
 4 3.1 ± 0.9 2.9 ± 0.6 0.769
 7 5.2 ± 0.5 3.6 ± 0.9 0.011
 10 10.3 ± 2.2 3.7 ± 0.6 0.002
 20 7.4 ± 0.8 4.4 ± 0.6 < 0.001
 30 4.3 ± 0.8 6.8 ± 0.6 0.001
 40 3.4 ± 0.7 9.9 ± 1.2 < 0.001
 50 2.6 ± 0.6 6.6 ± 0.6 < 0.001
 60 1.7 ± 0.8 3.5 ± 0.8 0.008
  1. Data presented as the mean amount of lidocaine in ng/1 mg bone
  2. p value compares lidocaine versus lidocaine with epinephrine
  3. Unpaired t-test or Welch’s test if unequal variance used to compare means
  4. SD standard deviation