Predicting dental caries increment using salivary biomarkers in a remote Indigenous Australian child population

BMC Oral Health

Table 3 Univariate analysis with caries increment at 2 years as the outcome variable and salivary characteristics as explanatory variables

Variable	Incipient caries (ICDAS 1 to 2)			Advanced caries (ICDAS 3 to 6)
	B (SE)	IRR (95%CI)	p	B (SE)	IRR (95% CI)	p
Sex
Male	0.11 (0.16)	1.12 (0.82–1.51)	0.47	0.09 (0.17)	1.09 (0.77–1.55)	0.61
Female	0^a			0^a
Comparison versus experimental; group
Experimental group	− 0.23 (0.15)	0.80 (0.59–1.07)	0.13	− 0.38 (0.17)	0.67 (0.48–0.95)	0.02
Comparison group	0^a			0^a
Baseline caries status	0.01 (0.01)	1.01 (0.99–1.02)	0.31	0.02 (0.01)	1.02 (1.01–1.04)	0.02
Salivary pH at baseline	− 0.12 (0.20)	0.88 (0.60–1.30)	0.53	− 0.02 (0.22)	0.97 (0.63–1.50)	0.91
Salivary flowrate per minute at baseline	0.08 (0.18)	1.08 (0.76–1.53)	0.66	− 0.86 (0.22)	0.43 (0.27–0.65)	0.000
Total buffering capacity at baseline	− 0.05 (0.05)	0.95 (0.86–1.05)	0.35	0.06 (0.05)	1.06 (0.95–1.18)	0.27
Salivary MS levels at baseline
≥ 10^5 CFU/ml saliva	0.42 (0.19)	1.53 (1.03–2.24)	0.03	0.50 (0.23)	1.66 (1.04–2.65)	0.03
< 10^5 CFU/ml saliva	0^a			0^a
Salivary LB levels at baseline
≥ 10^5 CFU/ml saliva	0.35 (0.18)	1.42 (0.99–2.05)	0.06	0.61 (0.21)	1.84 (1.20–2.80)	0.004
< 10^5 CFU/ml saliva	0^a			0^a
Salivary yeast counts
Moderate or heavy	0.03(0.24)	0.97 (0.60–1.56)	0.90	− 0.42(0.31)	0.65 (0.35–1.18)	0.16
None or light	0^a			0^a

ISSN: 1472-6831