Serum 8-isoprostane levels in patients with resistant oral lichen planus before and after treatment with lycopene: a randomized clinical trial

Table 1 Changes in Numeric rating scale (NRS) in both study groups at all assessment times

NRS	Lycopene group (n = 10)	Corticosteroids group (n = 10)	T-test p value
NRS	Mean ± SD		T-test p value
Baseline	5.90 ± 1.85^a	5.60 ± 1.43^a	p = 0.69
4 weeks	3.30 ± 1.42^b	2.80 ± 1.23^b	p = 0.41
8 weeks	2.10 ± 1.20^b	3.00 ± 1.56^b	p = 0.17
Repeated measures ANOVA p value	p < 0.001*	p < 0.001*

^a,bDifferent superscripted letters denote statistically significant differences between different time points in each group using Bonferroni adjustment for multiple pairwise comparisons
SD, standard deviation; n, number of patients
*Statistically significant at p value < 0.05

ISSN: 1472-6831