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Table 3 Serum levels of 8-isoprostane in both study groups at baseline and after 8 weeks

From: Serum 8-isoprostane levels in patients with resistant oral lichen planus before and after treatment with lycopene: a randomized clinical trial

8-isoprostane serum levels

Lycopene group (n = 10)

Corticosteroids group (n = 10)

Mann–Whitney U

p value

Mean ± SD

Median (IQR)

Baseline

96.21 ± 35.06

101.90 (60.80, 114.68)

108.73 ± 46.11

95.35 (62.05, 162.00)

p = 0.63

Week 8

59.94 ± 4.04

58.35 (57.65, 60.48)

93.65 ± 38.74

78.90 (62.40, 120.80)

p < 0.001*

Paired t-test p value

p = 0.01*

p = 0.45

 
  1. SD, standard deviation; IQR, inter quartile range; n number of patients
  2. *Statistically significant at p value < 0.05