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Table 3 Serum levels of 8-isoprostane in both study groups at baseline and after 8 weeks

From: Serum 8-isoprostane levels in patients with resistant oral lichen planus before and after treatment with lycopene: a randomized clinical trial

8-isoprostane serum levels Lycopene group (n = 10) Corticosteroids group (n = 10) Mann–Whitney U
p value
Mean ± SD
Median (IQR)
Baseline 96.21 ± 35.06
101.90 (60.80, 114.68)
108.73 ± 46.11
95.35 (62.05, 162.00)
p = 0.63
Week 8 59.94 ± 4.04
58.35 (57.65, 60.48)
93.65 ± 38.74
78.90 (62.40, 120.80)
p < 0.001*
Paired t-test p value p = 0.01* p = 0.45  
  1. SD, standard deviation; IQR, inter quartile range; n number of patients
  2. *Statistically significant at p value < 0.05