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Table 5 Logistic regression of risk factors of colonization throughout the treatment

From: An underestimated pitfall of oral candidiasis in head and neck cancer patients undergoing radiotherapy: an observation study

Patient characteristics

Univariate

Multivariate

OR (95 %CI)

p value

OR (95 %CI)

p value

Sex

    

   Male

1

   

 Female

1.42 (0.49–4.12)

0.523

  

Age

1.03 (0.99–1.08)

0.168*

1.06 (1.01–1.123)

0.021#

Underlying disease

    

 DM

0.52 (0.08–3.36)

0.496

  

 HT

0.78 (0.27–2.23)

0.641

  

Tumor site

    

 Nasopharynx

1

   

 Oropharynx

1.10 (0.33–3.60)

0.880

  

 Oral cavity

0.84 (0.26–2.69)

0.770

  

Radiotherapy option

    

 Postoperative RT

1

   

 Radical RT

1.15 (0.42–3.14)

0.790

  

Dose of radiotherapy (Gy)

1.08(1.01–1.16)

0.031*

  

CCRT

3.41 (1.16–9.99)

0.026*

4.29 (1.12–16.49)

0.034#

CCRT cycle

1.06 (0.64–1.78)

0.820

  

Type of chemotherapy agent

    

 Cisplatin

1

   

 Carboplatin

1.16 (0.36–3.80)

0.798

  

Personal history

    

 Smoking

    

  Never used

1

   

  Using currently

0.82 (0.26–2.56)

0.727

  

 Alcohol

    

  Never used

1

   

  Using urrently

1.54 (0.58–4.09)

0.387

  

Oral status

    

 Oral hygiene

    

  Excellent/good

1

   

  Fair/poor

0.68 (0.20–2.25)

0.527

  

 Denture wearer

0.41 (0.10–1.68)

0.216

  

Mouthwash using

    

 Non-benzydamine HCl

1

   

 Benzydamine HCl

1.05 (0.35–3.10)

0.934

  

2% viscous lidocaine solution using

2.91 (1.03–8.18)

0.043*

3.62 (1.15–11.34)

0.027#

Xerostomia

3.51 (0.74–16.70)

0.115*

  

Mucositis

2.85 (1.01–8.03)

0.048*

  

Candida colonization before RT

4.32 (1.32–14.14)

0.016*

  
  1. *p < 0.25, # significant risk factors
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BMC Oral Health

ISSN: 1472-6831

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