|  | Day 0 | Day 28 | L | N | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L | N | P | L | N | P | Day 0 | Day 28 | P | Day 0 | Day 28 | P | ||
TNF-α | Zr | 4.25 ± 1.50 | 3.66 ± 1.40 | 0.550 | 7.85 ± 3.98 | 4.09 ± 1.64 | 0.022* | 4.25 ± 1.50 | 7.85 ± 3.98 | 0.127 | 3.66 ± 1.40 | 4.09 ± 1.64 | 0.725 |
Ti | 3.32 ± 1.03 | 4.67 ± 2.36 | 0.468 | 6.95 ± 2.27 | 5.48 ± 1.95 | 0.343 | 3.32 ± 1.03 | 6.95 ± 2.27 | 0.011* | 4.67 ± 2.36 | 5.48 ± 1.95 | 0.585 | |
P | 0.535 | 0.482 | Â | 0.556 | 0.369 | Â | 0.535 | 0.556 | Â | 0.482 | 0.369 | Â | |
IL-1β | Zr | 1.25 ± 0.22 | 1.32 ± 0.26 | 0.642 | 1.52 ± 0.28 | 1.12 ± 0.34 | 0.393 | 1.25 ± 0.22 | 1.52 ± 0.28 | 0.538 | 1.32 ± 0.26 | 1.12 ± 0.34 | 0.525 |
Ti | 1.11 ± 0.18 | 1.23 ± 0.16 | 0.426 | 1.67 ± 0.35 | 1.00 ± 0.20 | 0.173 | 1.11 ± 0.18 | 1.67 ± 0.35 | 0.396 | 1.23 ± 0.16 | 1.00 ± 0.20 | 0.429 | |
P | 0.349 | 0.542 | Â | 0.758 | 0.809 | Â | 0.349 | 0.758 | Â | 0.542 | 0.809 | Â |