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Table 2 Differences in adjusted value (mean ± standard error) of S100A8 (pg/ml) and S100A9 (pg/ml) by periodontitis status (n = 149)

From: S100A8 and S100A9 in saliva, blood and gingival crevicular fluid for screening established periodontitis: a cross-sectional study

Protein

Periodontitis status

p value

Sample

No-Stage I (n = 50)

Stage II (n = 76)

Stage III–IV (n = 23)

S100A8 (pg/ml)

Saliva

5348.53 ± 794.80a

8152.65 ± 607.91b

9512.13 ± 1132.64b

0.007

GCF

416.43 ± 56.02a

146.84 ± 42.85b

187.40 ± 79.84b

0.002

Blood

497,523.22 ± 35,568.06

579,163.20 ± 27,204.67

648,641.67 ± 50,687.01

0.057

S100A9 (pg/ml)

Saliva

1430.58 ± 393.97

1380.99 ± 301.33

1780.66 ± 561.44

0.820

GCF

230.12 ± 36.41a

98.17 ± 27.85b

63.59 ± 51.89b

0.011

Blood

162,405.26 ± 4146.13

172,167.34 ± 3171.22

166,097.21 ± 5908.53

0.189

  1. Bold denotes statistical significance at p < 0.05
  2. p values: obtained by ANCOVA for adjusted mean and standard error
  3. Values were adjusted for age, sex, education, smoking, drinking, obesity, diabetes, hypercholesterolemia, and hypertension by ANCOVA in GLM. Superscript denotes same groups according to Bonferroni’s post hoc multiple comparison test