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Table 1 Studies and population characteristics

From: Periodontal status and chronic obstructive pulmonary disease (COPD) exacerbations: a systematic review

References

Type of study

Location

Number/gender

Age (years)

Follow-up

Periodontal assessment

Intervention exposure

COPD diagnosis

Funding

Zhou et al. [33]

Cross-sectional

China

306

210 M

96 F

Mild: 65.5 ± 8.62 Mod: 64.4 ± 10.2 Severe: 63.1 ± 9.24 Very Severe:62.3 ± 11.0

None

Periodontal examination (PI, BI, PPD, CAL) and Number of teeth

Diagnostic criteria not reported

Poor periodontal health

GOLD Criteria

ISTCRG

NNSFC

Liu et al. [34]

Cross-sectional

China

392

287 M

105 F

Cases: 64.3 ± 10.1 Controls: 63.6 ± 9.7

None

Periodontal examination

(PI, BI, PPD, CAL)

Diagnostic criteria was: PD > 3 mm, CAL > 4 mm used to diagnose periodontal disease

Interview re oral hygiene behaviours

Poor periodontal health

GOLD Criteria

NNSFC

NSFB

BSTPF

Agado et al. [40]

Randomised control trial

USA

30

20 M

10 F

UI:62 ± 7.76 HI:68 ± 7.20 Control:62 ± 8.33

None

Periodontal examination (PI, CAL) Diagnostic criteria was: > 6 teeth and minimum mean CAL of 1.5 mm used to diagnose periodontal disease

Periodontal treatment

Not stated

ISUIM

Barros et al. [37]

Prospective cohort

USA

1635

930 M

705F

Events (No): 66.0 (5.13); Events (Yes): 63.9 (5.69)

5 years

Periodontal examination (PPD, CAL)**

Periodontal health/edentualism

GOLD Criteria

GSK

Kucukcokun et al. [39]

Clinical trial

Turkey

40

35 M

5 F

Intervention: 61.8 ± 7.57 Control: 57.85 ± 12.09

1 year

Periodontal examination (PI, GI, PPD, BOP and CAL)#

Periodontal treatment

GOLD Criteria

NS

Zhou et al. [38]

Randomised control trial

China

60

47 M

13 F

Intervention: 63.9 ± 9.44, 65.3 ± 7.54

Control: 68.0 ± 7.64

2 years

Periodontal examination (PI, BI, PPD, CAL)*

Periodontal treatment

GOLD Criteria

NNSFC

AbdelHalim et al. [35]

Cross-sectional

Egypt

250

250 M

0 F

Cases: 56.75 ± 10.42 Controls: 55.28 ± 9.12

None

Periodontal examination

(PI, BI GI, PPD and CAL)##

Poor periodontal health

GOLD Criteria

NS

Baldomero et al. [36]

Case–control

USA

136

136 M

0 F

56 had dental exam

Cases: 66.8 (7.2)

Controls: 67.5 (5.5)

None

Oral health questionnaire & Periodontal examination (PI, BOP, GI, PPD and CAL)##

Poor periodontal health

ACP, ACCP and ATS

NHLBI

VACDA

  1. PI, plaque index; BI, bleeding index; BOP, bleeding on probing; GI, gingival index; PPD, probing pocket depth; CAL, clinical attachment level); N/A, Not available; QoL, quality of life; SGRQ, St George’s Respiratory Questionnaire; OHIP, 5-Oral health impact profile-5; GOLD, Global Initiative for Obstructive Lung Disease; ACP, American College of Physicians; ACCP, American College of Chest Physicians; ATS, American Thoracic Society criteria; NHLBI, National Heart, Lung and Blood Institute; VACDA, Veterans Affairs Career Development Award; GSK, GlaxoSmithKline; NNSFC, National Natural Science Foundation of China; NSFB, Natural Science Foundation of Beijing; BSTPF, Beijing Science and Technology Programme Fund; NS, not stated; ISTCRG, International Science and Technology Cooperation Research Grant, Beijing Municipal Science and Technology Commission; ISUIM, Idaho State University Intra Mural
  2. **JCDC + AAP-joint Center for Disease Control/American Association of Periodontology
  3. #1999 AAPW-1999 American Academy of Periodontology Workshop guidelines
  4. ##AAPTFR- American Academy of Periodontology Task Force Report