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Table 3 Summary of secondary outcomes of hospitalisations and quality of life

From: Periodontal status and chronic obstructive pulmonary disease (COPD) exacerbations: a systematic review

Study

Outcome and how measured

Results summary

Zhou et al. [33]

QoL assessed by SGRQ scores

After adjusting for age, gender, body mass index, and smoking status, missing teeth was significantly associated with symptom score (p = 0.030) and activity score (p = 0.033) and plaque index was significantly associated with symptom score (p = 0.007)

Agado et al. [40]

QoL measured by SGRQ-A and self-assessment of overall current health in COPD patients receiving periodontal treatment and control group with no treatment

SGRQ–A and Illness Questionnaire scores showed no significant differences between groups in quality of life or illness following periodontal treatment. Total SGRQ scores decreased among groups but not significantly (p = 0.138)

Barros et al. [37]

Frequency of COPD-related events and hospitalisation from hospital records

Periodontal disease and edentulism are associated with increased risk of COPD event requiring hospitalisation but after adjusting for age, race, centre, gender, education, hypertension, BMI and smoking only edentulism remained significant (Hazard Ratio 2.28, 95% CI 1.46–3.56)

Kucukcoskun et al. [39]

Hospitalisation confirmed by a physician

There were 7 hospitalisations in the test group and 12 in the control group over 12 months of follow-up

AbdelHalim et al. [35]

Self-reported number of hospitalisations

All periodontal health parameters correlate significantly with the number of hospitalisations per year (p < 0.001)

Baldomero et al. [36]

St. George’s Respiratory Questionnaire (SGRQ) and OHIP-5), hospitalisations

There was a strong association between OHIP-5 items, difficulty chewing (OR 2.57, p = 0.02), painful ache in the mouth (OR 5.4, p < 0.001), appearance (OR 3.1, p = 0.003), less flavour (OR 3.5, p = 0.005) and difficulty doing jobs (OR 7.3, p < 0.001) worse respiratory health scores after adjusting for inhaler use and FEV1% predicted

There was a non-significant trend towards more severe COPD exacerbations requiring emergency room visits and/or hospitalisations in those with worse periodontal health indices