Fig. 4

Expression levels of FimA-specific (a) and HA2-specific (b) secretory IgA antibodies in the saliva of SD rats at week 0–8, which were immunized with nothing (group A), 100 ug of saline (group B), 100 ug of pVAX1 (group C), 100 ug of pVAX1-HA2-fimA (group D), 100 ug of pVAX1-HA2-fimA/IL-15 (group E), and 100 ug of pVAX1-HA2-fimA+CpG-ODN 1826 (30 μg) (group F), respectively. Asterisk represents a significant difference between group F and the other groups, respectively, *P < 0.05