Fig. 5From: CpG immunostimulatory oligodeoxynucleotide 1826 as a novel nasal ODN adjuvant enhanced the protective efficacy of the periodontitis gene vaccine in a periodontitis model in SD ratsDetection of rat alveolar bone damage by stereomicroscopy and immunohistochemical staining. Buccal and palatal alveolar bone loss were measured along the long axis of the teeth in a group A (blank), b group B (100 ug of saline), c group C (100 ug of pVAX1), d group D (100 ug of pVAX1-HA2-fimA), e group E (100 ug of pVAX1-HA2-fimA/IL-15), and f group F (100 ug of pVAX1-HA2-fimA+CpG-ODN 1826 (30 μg)), respectively. g Statistical results. Asterisk represents a significant difference between group F and group B–E, respectively, *P < 0.05Back to article page