Fig. 7From: CpG immunostimulatory oligodeoxynucleotide 1826 as a novel nasal ODN adjuvant enhanced the protective efficacy of the periodontitis gene vaccine in a periodontitis model in SD ratsExpression of RANKL in the periodontal tissue of the maxillary second molars of SD rats in group A-F. a group A (blank), b group B (100 ug of saline), c group C (100 ug of pVAX1), d group D (100 ug of pVAX1-HA2-fimA), e group E (100 ug of pVAX1-HA2-fimA/IL-15), and f group F [100 ug of pVAX1-HA2-fimA+CpG-ODN 1826 (30 μg)], g Statistical results. Asterisk represents a significant difference between group F and group B–E, respectively, *P < 0.05. Scale bars represent 100 μm. Magnification, 200×Back to article page