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Fig. 2 | BMC Oral Health

Fig. 2

From: Effects of iRoot SP on osteogenic differentiation of human stem cells from apical papilla

Fig. 2

Cell proliferation and migration capacity of hSCAPs cultured with iRoot SP extract at various concentrations. A hSCAP proliferation was measured by CCK-8 assay. The results show that 0.2 mg/mL extract improves the proliferation level at 3 and 5 days compared with the control, and that there is no significant difference between the 0.02 mg/mL, 2 mg/mL, and control groups. B Cell migration processes as observed under a microscope. C Wound-closure percentages of hSCAPs cultured in iRoot SP at 12 h. Scratch-wound-healing assays show that the migration capacity of hSCAPs cultured in 0.02 and 0.2 mg/mL iRoot SP extract were significantly increased compared with the control group. *P < 0.05, **P < 0.01, and ***P < 0.005. Error bars: mean ± standard deviation

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