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Table 4 BDNF c.196G > A and NTRK2 c.1397-31392G > A alleles association and correlation of genotypes with AB and clinical presentation

From: Polymorphic variants in genes related to stress coping are associated with the awake bruxism

Parameter BDNF c.196G > A (rs6265) NTRK2 c.1397-31392G > A (rs1867283)
n = 104
GG
(n = 47)
GA
(n = 55)
AA
(n = 2)
[GG + GA] versus [AA]
OR, CI
P value
[GG] versus [GA + AA]
OR, CI
P value
[G] versus [A]
OR, CI
[A] versus [G]
OR, CI
GG
(n = 32)
GA
(n = 52)
AA
(n = 20)
[GG + GA] versus [AA]
OR, CI
P value
[GG] versus [GA + AA]
OR, CI
P value
[G] versus [A]
OR, CI
[A] versus [G]
OR, CI
P value P value
The perceived stress level in sten scale (mean ± SD) 7.13 ± 1.15 7.11 ± 1.10 7.50 ± 2.12 NA NA NA NA 7.22 ± 1.10 7.10 ± 1.16 7.25 ± 1.16 NA NA NA NA
P = 0.840 P = 0.629
Attrition of anterior teeth
n = 78
40 (51.3%) 38 (48.7) 0 (0%) OR = 1.40
CI = [0.07–30.17]
P = 0.460
OR = 2.86
CI = [1.08–7.57]
P = 0.031
OR = 2.10
CI = [1.08–4.09]
OR = 0.48
CI = [0.25–0.92]
26 (33.3%) 38 (48.7%) 14 (18%) OR = 0.73
CI = [0.25–2.15]
P = 0.566
OR = 1.67
CI = [0.60–4.66]
P = 0.326
OR = 1.36
CI = [0.73–2.56]
OR = 0.73
CI = [0.39–1.38]
P = 0.026 P = 0.333
Attrition of posterior teeth
n = 44
28 (63.6%) 16 (36.4%) 0 (0%) OR = 0.26
CI = [0.01–5.62]
P = 0.221
OR = 3.78
CI = [1.66–8.58]
P = 0.001
OR = 2.51
CI = [1.30–4.85]
OR = 0.40
CI = [0.21–0.77]
14 (31.8%) 26 (59.1%) 4 (9.1%) OR = 0.28
CI = [0.09–0.89]
P = 0.025
OR = 1.09
CI = [0.47–2.53]
P = 0.843
OR = 1.49
CI = [0.85–2.60]
OR = 0.67
CI = [0.39–1.18]
P = 0.005 P = 0.164
Enamel cracks
n = 82
43 (52.5%) 37 (45.1%) 2 (2.4%) OR = 1.40
CI = [0.07–30.17]
P = 0.460
OR = 4.96
CI = [1.55–15.94]
P = 0.004
OR = 2.08
CI = [1.03–4.17]
OR = 0.48
CI = [0.24–0.97]
22 (26.8%) 44 (53.7%) 16 (19.5%) OR = 1.09
CI = [0.32–3.67]
P = 0.888
OR = 0.44
CI = [0.17–1.16]
P = 0.093
OR = 0.66
CI = [0.33–1.32]
OR = 1.51
CI = [0.76–3.00]
P = 0.038 P = 0.237
Impressions on the tongue
n = 70
33 (47.2%) 36 (51.4%) 1 (1.4%) OR = 0.48
CI = [0.03–7.89]
P = 0.598
OR = 1.27
CI = [0.56–2.92]
P = 0.566
OR = 1.20
CI = [0.64–2.26]
OR = 0.83
CI = [0.44–1.57]
16 (22.9%) 38 (54.2%) 16 (22.9%) OR = 2.22
CI = [0.68–7.25]
P = 0.178
OR = 0.33
CI = [0.14–0.80]
P = 0.012
OR = 0.48
CI = [0.26–0.88]
OR = 2.09
CI = [1.14–3.84]
P = 0.575 P = 0.016
  1. In bold were marked statistically significant and borderline significant results (P < 0.05). No corrections for the multiple statistical testing were made
  2. [GG + GA] versus [AA]—dominant model, risk allele: G; [GG] versus [GA + AA]—recessive model, risk allele: A