Table 4 BDNF c.196G > A and NTRK2 c.1397-31392G > A alleles association and correlation of genotypes with AB and clinical presentation
From: Polymorphic variants in genes related to stress coping are associated with the awake bruxism
Parameter | BDNF c.196G > A (rs6265) | NTRK2 c.1397-31392G > A (rs1867283) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n = 104 | ||||||||||||||
GG (n = 47) | GA (n = 55) | AA (n = 2) | [GG + GA] versus [AA] OR, CI P value | [GG] versus [GA + AA] OR, CI P value | [G] versus [A] OR, CI | [A] versus [G] OR, CI | GG (n = 32) | GA (n = 52) | AA (n = 20) | [GG + GA] versus [AA] OR, CI P value | [GG] versus [GA + AA] OR, CI P value | [G] versus [A] OR, CI | [A] versus [G] OR, CI | |
P value | P value | |||||||||||||
The perceived stress level in sten scale (mean ± SD) | 7.13 ± 1.15 | 7.11 ± 1.10 | 7.50 ± 2.12 | NA | NA | NA | NA | 7.22 ± 1.10 | 7.10 ± 1.16 | 7.25 ± 1.16 | NA | NA | NA | NA |
P = 0.840 | P = 0.629 | |||||||||||||
Attrition of anterior teeth n = 78 | 40 (51.3%) | 38 (48.7) | 0 (0%) | OR = 1.40 CI = [0.07–30.17] P = 0.460 | OR = 2.86 CI = [1.08–7.57] P = 0.031 | OR = 2.10 CI = [1.08–4.09] | OR = 0.48 CI = [0.25–0.92] | 26 (33.3%) | 38 (48.7%) | 14 (18%) | OR = 0.73 CI = [0.25–2.15] P = 0.566 | OR = 1.67 CI = [0.60–4.66] P = 0.326 | OR = 1.36 CI = [0.73–2.56] | OR = 0.73 CI = [0.39–1.38] |
P = 0.026 | P = 0.333 | |||||||||||||
Attrition of posterior teeth n = 44 | 28 (63.6%) | 16 (36.4%) | 0 (0%) | OR = 0.26 CI = [0.01–5.62] P = 0.221 | OR = 3.78 CI = [1.66–8.58] P = 0.001 | OR = 2.51 CI = [1.30–4.85] | OR = 0.40 CI = [0.21–0.77] | 14 (31.8%) | 26 (59.1%) | 4 (9.1%) | OR = 0.28 CI = [0.09–0.89] P = 0.025 | OR = 1.09 CI = [0.47–2.53] P = 0.843 | OR = 1.49 CI = [0.85–2.60] | OR = 0.67 CI = [0.39–1.18] |
P = 0.005 | P = 0.164 | |||||||||||||
Enamel cracks n = 82 | 43 (52.5%) | 37 (45.1%) | 2 (2.4%) | OR = 1.40 CI = [0.07–30.17] P = 0.460 | OR = 4.96 CI = [1.55–15.94] P = 0.004 | OR = 2.08 CI = [1.03–4.17] | OR = 0.48 CI = [0.24–0.97] | 22 (26.8%) | 44 (53.7%) | 16 (19.5%) | OR = 1.09 CI = [0.32–3.67] P = 0.888 | OR = 0.44 CI = [0.17–1.16] P = 0.093 | OR = 0.66 CI = [0.33–1.32] | OR = 1.51 CI = [0.76–3.00] |
P = 0.038 | P = 0.237 | |||||||||||||
Impressions on the tongue n = 70 | 33 (47.2%) | 36 (51.4%) | 1 (1.4%) | OR = 0.48 CI = [0.03–7.89] P = 0.598 | OR = 1.27 CI = [0.56–2.92] P = 0.566 | OR = 1.20 CI = [0.64–2.26] | OR = 0.83 CI = [0.44–1.57] | 16 (22.9%) | 38 (54.2%) | 16 (22.9%) | OR = 2.22 CI = [0.68–7.25] P = 0.178 | OR = 0.33 CI = [0.14–0.80] P = 0.012 | OR = 0.48 CI = [0.26–0.88] | OR = 2.09 CI = [1.14–3.84] |
P = 0.575 | P = 0.016 | |||||||||||||