Fig. 1

Effect of periodontitis in alveolar bone loss. (A) Representative images of right and left jaws of buccal and lingual surfaces of WKY rats and SHR, with and without PD. (B) Linear and area of the alveolar bone loss was measured macroscopically by mean of the lingual and buccal surfaces of the right and left jaws. The yellow dashed lines indicate the three distances measured in the teeth and yellow solid lines indicate alveolar bone loss area. Quantifications were performed using ImageJ 1.50i software, a version of Wayne Rasband, National Institutes of Health, USA (https://imagej.nih.gov/ij/). Data are mean ± SEM. * P < 0.05 compared to sham operated WKY. ^#P < 0.05 compared to sham operated SHR. Wistar Kyoto rats without periodontal disease (WKY + Sham, n = 7); Wistar Kyoto rats with periodontal disease (WKY + PD, n = 10); Spontaneously hypertensive rats without periodontitis (SHR + Sham, n = 7); Spontaneously hypertensive rats with periodontitis (SHR + PD, n = 6). M1: lower first molar; M2: second lower molar; and M3: third molar