Fig. 3

Plasma nitrate and inflammatory cytokine in the myocardial tissue. Bar Graphs show: Panel A, plasma nitrate level (indirect measurement of nitric oxide); Panel B, interleukin-1 beta (IL-1β) myocardial tissue concentration; Panel C, correlation between linear alveolar bone boss and plasma nitrate concentration; and Panel D, correlation between linear alveolar bone boss and IL-1β myocardial tissue concentration. *P < 0.05 compared to WKY + Sham and ^#P < 0.05 compared to WKY + PD. Wistar Kyoto rats without periodontal disease (WKY + Sham, n = 6); Wistar Kyoto rats with periodontal disease (WKY + PD, n = 6–8); Spontaneously hypertensive rats without periodontitis (SHR + Sham, n = 5–6); Spontaneously hypertensive rats with periodontitis (SHR + PD, n = 5–7)