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Fig. 4 | BMC Oral Health

Fig. 4

From: Nicotine regulates autophagy of human periodontal ligament cells through α7 nAchR that promotes secretion of inflammatory factors IL-1β and IL-8

Fig. 4

Effects of nicotine and/or 3-MA on the production of IL-1β and IL-8. A The relative expression of IL-1β mRNA from hPDLCs after nicotine and/or 3-MA treatment; B The relative expression of IL-8 mRNA from hPDLCs after nicotine and/or 3-MA treatment; C Release of IL-1β from hPDLCs after nicotine and/or 3-MA application; D Release of IL-8 from hPDLCs after nicotine and/or 3-MA application. Data from three independent experiments were presented as mean ± SD (*p < 0.05, **p < 0.005, ***p < 0.001, ****p < 0.0001)

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