Efficacy of a new-generation platelet-rich fibrin in the treatment of periodontal intrabony defects: a randomized clinical trial

Table 4 Within group comparisons/intergroup changes (significance: p < 0.05)

	Baseline	6 months postop	p	Diff	p
PD
A-PRF+	8.27 ± 1.58	4.67 ± 0.62	p < 0.0001	−3.6 ± 1.68	p = 0.0000
EMD	8.13 ± 1.60	4.67 ± 0.62	p < 0.0001	−3.46 ± 1.30	p = 0.0000
		p = 0.999
Cohen's d		d = −0.092
GR
A-PRF+	2.67 ± 1.88	3.93 ± 2.73	p < 0.0025	1.26 ± 1.33	p = 0.0025
EMD	2.47 ± 1.46	3.33 ± 1.58	p < 0.0044	0.86 ± 0.99	p = 0.0044
		p = 0.,469
Cohen's d		d = 0.352
CAL
A-PRF+	10.93 ± 2.7	8.6 ± 2.56	p < 0.0001	−2.33 ± 1.588	p = 0.0001
EMD	10.60 ± 1.76	8.00 ± 1.77	p < 0.0001	−2.6 ± 1.18	p = 0.0000
		p = 0,461
Cohen's d		d = 0.197
BS
A-PRF+	9.60 ± 1.68	5.67 ± 0.89	p < 0,0001	−3.93 ± 1.98	p = 0.0000
EMD	9.47 ± 1.68	5.67 ± 0.81	p < 0,0001	−3.8 ± 1.56	p = 0.0000
		p = 0.999
Cohen's d		d = −0.077

PD Probing depth, GR gingival recession, CAL clinical attachment level, BS bone sounding

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