Table 1 Characteristics of included studies
References | Country | Study design | Sample size | Sex | Age | Type of platelet concentrates | Method of application | Outcome | Result |
|---|---|---|---|---|---|---|---|---|---|
Alhussaini et al. [6] | Iraq | CCTa (split mouth) | 32 | Female 59.4% | 25–66, 48.6 ± 10.3 | PRFb | PRF clot placed in the implant sites | Implant stability (ISQc) | There was no statistically significant difference at 6 months (P = 0.348) and 12 months (P = 0.642) |
Boora et al. [25] | India | RCTd | 20 | Female 25.0% | 18–33, 24.6 | PRF | PRF membrane placed in the implant sites | MBLe | The MBL of the test group was significantly lower than that of the control group within 3 months |
Diana et al. [42] | India | RCT | 31 | Female 41.9% | 28.5 | PRF | PRF membrane placed in the implant sites | Implant stability (ISQ) | There was no statistically significant difference at 3 months (P = 0.645) |
Ergun et al. [41] | Turkey | CCT | 32 | Female 53.1% | 44.2 ± 12.5 | PRPf | Dipping the implant in PRP liquid before insertion Injected into the implant socket | Implant stability (ISQ) | There was no statistically significant difference in all periods |
Khan et al. [43] | India | RCT | 17 | Female 35.3% | NR | PRF | Dipping the implant in PRF liquid before insertion PRF membrane placed in the implant sites | MBL | There was no statistically significant Difference between the two groups at all follow-up intervals |
Khan et al. [28] | Pakistan | RCT | 12 | NRg | NR | PRP | Injected into the implant socket | MBL | There was no statistically significant Difference between the two groups at all follow-up intervals |
Kundu et al. [17] | India | RCT | 30 | Female 56.7% | 18–56, 33.93 ± 11.25 | PRP | Dipping the implant in PRP liquid before insertion | Implant stability (PTVh), MBL | For PTV, there was no statistically significant difference at 1 month (P = 0.107) and 3 months (P = 0.153) PRP had no significant effect on bone height changes at 1 month and 3 months (P > 0.05) |
Monov et al. [40] | Austria | CCT (split mouth) | 10 | Female 60.0% | 53–80, 67 | PRP | Dipping the implant in PRP liquid before insertion Injected into the implant socket | Implant stability (Hz) | Except for the first week, there was no statistically significant difference between the two sides (P > 0.05) |
Öncü et al. [21] | Turkey | RCT | 20 | Female 30.0% | 44.2 ± 12.5 | PRF | Dipping the implant in PRF liquid before insertion PRF membrane placed in the implant sites | Implant stability (ISQ) | ISQ in the test group was significantly higher than that in the control group at the end of the first week (P = 0.002) and the fourth week (P = 0.001) |
Öncü et al. [22] | Turkey | RCT (split mouth) | 26 | Female 38.5% | 40.2 ± 11.5 | PRF | PRF membrane placed in the implant sites | Implant stability (PTV), MBL | Except for the third month, ISQ in the test side was significantly higher than that in the control side at 1 week and 1 month (P ≤ 0.002) PRF can significantly reduce marginal bone resorption after at least one year (P ≤ 0.05) |
Koyuncu et al. [16] | Turkey | CCT | 12 | Female 58.3% | 53–86 | CGFi | CGF membrane placed in the implant sites | Implant stability (ISQ) | There was no statistically significant Difference between the two groups After 1, 2, and 4 weeks (P > 0.050) |
Pirpir et al. [1] | Turkey | RCT | 12 | Female 58.3% | 20–68, 44 | CGF | Dipping the implant in CGF liquid before insertion CGF membrane placed in the implant sites | Implant stability (ISQ) | ISQ in the test group was significantly higher at week 1 and week 4 (P < 0.050) |
Tabrizi et al. [23] | Iran | RCT (split mouth) | 20 | Female 55.0% | 39.60 ± 6.74 | PRF | PRF fibrin matrix placed in the implant sites | Implant stability (ISQ) | The PRF side got significantly higher ISQ at 2 weeks (P = 0.040), 4 weeks (P = 0.014), and 6 weeks (P = 0.027) after insertion |
Torkzaban et al. [24] | Iran | CCT | 10 | Female 50.0% | 26–60, 45.3 | PRF | Dipping the implant in PRF liquid before insertion PRF membrane placed in the implant sites | Implant stability (ISQ) | ISQ in the test group was significantly higher at the end of the first week (P = 0.004) and the first month (P = 0.015) |