Effects of platelet concentrates on implant stability and marginal bone loss: a systematic review and meta-analysis

Table 2 The subgroup analysis of meta-analysis on implant stability at 1 week after insertion

Group	Number of studies	SMD^a (MD^b)	95% CI^c	Heterogeneity
Group	Number of studies	SMD^a (MD^b)	95% CI^c	P_{heterogeneity}	I² (%)
Type of platelet concentrates
PRF^d	3	5.53	(2.19–8.88)	0.21	35
CGF^e	2	4.71	(0.77–8.64)	0.21	36
PRP^f	1	1.22	(− 1.51 to 3.95)	–	–
Method of application
Dipping the implant in the liquid before insertion	4	4.51	(1.79–7.22)	0.02	68
Only placed in the implant sites	2	3.28	(− 1.71 to 8.27)	0.39	0
Study design
RCT^g	3	6.42	(4.20–8.64)	0.55	0
CCT^h	3	2.56	(0.71–4.41)	0.35	5

^a standardized mean difference; ^b mean difference; ^c confidence Interval; ^d platelet-rich fibrin; ^e concentrated growth factor; ^f platelet-rich plasma; ^g randomized controlled trial; ^h clinical controlled trial

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