Skip to main content
Fig. 5 | BMC Oral Health

Fig. 5

From: FERMT1 knockdown inhibits oral squamous cell carcinoma cell epithelial-mesenchymal transition by inactivating the PI3K/AKT signaling pathway

Fig. 5

IGF-1 treatment activated the PI3K/AKT signaling pathway in si-FERMT1-transfected Tca8113 and SCC15 cells. OSCC cells were treated with 5 ng/ml recombinant human TGF-β1 protein. A PI3K, total (t)-AKT mRNA expression were analyzed by qRT-PCR after IGF-1 treatment at 24 h in si-FERMT1-transfected Tca8113 and SCC15 cells. B The representative image of western blot. C PI3K, t-AKT, and phosphorylated (p)-AKT protein levels were analyzed by western blotting after IGF-1 treatment at 24 h in si-FERMT1-transfected Tca8113 and SCC15 cells. ***P < 0.001, si-FERMT1 + IGF-1 vs si-FERMT1 + PBS

Back to article page

BMC Oral Health

ISSN: 1472-6831

Contact us