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Table 3 Metabolite changes in the metabolic pathway analysis of periapical periodontitis

From: Metabolome and microbiome of chronic periapical periodontitis in permanent anterior teeth: a pilot study

 

Metabolic pathway

The total number of metabolites

The total number of

differential metabolites

Metabolites

P value

−Log(p) value

1

Aminoacyl-tRNA biosynthesis

48

9

L-Asparagine, L-Phenylalanine,

L-Serine, L-Methionine,

L-Valine, L-Alanine,

L-Tryptophan, L-Tyrosine,

L-Glutamine

0.00

21.47

2

Phenylalanine, tyrosine and tryptophan biosynthesis

4

2

L-Phenylalanine,

L-Phenylalanine

0.00

7.19

3

Alanine, aspartate and glutamate metabolism

28

3

L-Asparagine,

L-Alanine, L-Glutamate

0.00

5.63

4

Phenylalanine metabolism

10

2

L-Phenylalanine,

L-Tyrosine

0.01

5.22

5

Cysteine and methionine metabolism

33

3

L-Serine,

L-Methionine,

3-methylthiopropionate

0.01

5.16

6

Amino sugar and nucleotide sugar metabolism

37

3

N-Acetylmannosamine, N-acetyl-D-glucosamine

0.01

4.83