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Table 1 Clinical characteristics of the study population

From: Difference in oral microbial composition between chronic periodontitis patients with and without diabetic nephropathy

 

DM group

DN group

P value

Age, years

53.80 ± 12.08

58.00 ± 10.62

0.321

Male, n (%)

11 (73.33%)

7 (46.67%)

0.136

BMI (kg/m2)

26.25 ± 3.07

27.65 ± 4.88

0.356

Diabetes course (years)

7.20 ± 5.81

13.98 ± 6.98

0.007**

Smoking, n (%)

8 (52%)

6 (40%)

0.464

Biochemical parameters

 Urea nitrogen (mmol/L)

5.76 (4.75, 6.77)

7.27 (4.86, 9.14)

0.181

 Uric acid (μmol/L)

285.01 ± 101.90

390.53 ± 61.10

0.002**

 FBG (mmol/L)

9.46 ± 2.58

9.87 ± 3.49

0.712

 HbA1c (%)

8.31 ± 2.27

7.99 ± 1.29

0.639

 Urinary albumin (mg/L)

6.30 (5.00, 12.00)

48.60 (28.40, 293.40)

 < 0.001**

 Urinary creatinine (μmol/L)

53.10 (37.20, 90.50)

63.90 (32.20, 84.60

0.925

 ACR (mg/g)

13.12 (7.79, 25.64)

78.98 (38.55, 354.61)

0.001**

 eGFR (ml/L)

113.21 ± 24.25

85.51 ± 43.13

0.042*

Parameters of periodontitis

 PD (mm)

3.38 ± 0.95

3.37 ± 0.93

0.995

 BI

3.31 ± 0.68

2.99 ± 0.70

0.377

 CAL (mm)

4.64 ± 1.60

5.09 ± 2.00

0.216

 Remaining teeth numbers

24.67 ± 4.98

22.87 ± 5.96

0.377

  1. P-values calculated using two independent samples t test, Mann–Whitney U test, or Chi-squared test. P < 0.05 was statistically significant. *P < 0.05, **P < 0.01
  2. BMI, body mass index; LDL, low density lipoprotein; HDL, high density lipoprotein; FBG, fasting blood glucose; HbA1c, glycated hemoglobin; ACR, albumin creatinine ratio; eGFR, estimated glomerular filtration rate; PD, probing depth; BI, blooding index; CAL, clinical attachment loss