The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study

Table 3 Mean ± SD of cytokine (IL-6) expression (pg/mL) of all the groups at different time periods

Groups	0 h	24 h	7th day
CC	0.1693 ± 0.139	0.1119 ± 0.095	0.5476 ± 0.010
SC	0.2643 ± 0.186	0.8024 ± 0.634	0.9714 ± 0.557
ZE	0.8500 ± 0.603	18.7000 ± 0.622^†	25.4952 ± 0.307^†
ER	0.9071 ± 0.545	18.6809 ± 0.267^†	23.1476 ± 0.646
ZES	0.6167 ± 0.455	10.5190 ± 0.657	12.7048 ± 0.578
ERS	0.2833 ± 0.255	9.5571 ± 0.495	14.6810 ± 0.825

n = 3, (P > 0.05). ^†Statistically significant. (^†Represent the intergroup comparative values that are statistically significant against the control groups)
IL-6-Interleukin-6; pg/mL-picogram/millilitre
h-hours; CC-Cell control; SC-Solvent control; ZE-Zinc Oxide Eugenol sealer; ER-EndoREZ sealer; ZES & ERS- Simvastatin incorporated Zinc oxide eugenol and EndoREZ respectively

ISSN: 1472-6831