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Table 1 Characteristics of the included studies

From: Added effect of 1% topical alendronate in intra-bony and inter-radicular defects as part of step II periodontal therapy: a systematic review with meta-analysis and trial sequential analysis

Authors

 

Year

Follow-up

Design of the study

Type of defect

Type of intervention

Number of defects

Funding

Test

Control

Test

Control

 

Ipshita et al. [19]

India

2018

6–12 months

Parallel

Inter-radicular

SRP + ALN 1%

SRP + Placebo

30

30

Yes

Dutra et al. [21]

Brasil

2017

6 months

Split-mouth

Intra-bony

ALN 1%

Placebo

20

20

No

Sharma et al. [22]

India

2017

6 months

Parallel

Intra-bony

ALN 1%

Placebo

39

42

Yes

Pradeep et al. [25]

India

2017

6–9 months

Parallel

Intra-bony

ALN 1%

Placebo

30

30

Yes

Sharma and Pradeep [23]

India

2012

6 months

Parallel

Intra-bony

ALN 1%

Placebo

33

33

Yes

Sharma and Pradeep [24]

India

2012

6 months

Parallel

Intra-bony

ALN 1%

Placebo

26

26

Yes

Pradeep et al. [20]

India

2013

6–12 months

Parallel

Inter-radicular

ALN 1%

Placebo

29

28

Yes