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Table 2 Clinicopathological data of OSCC patients and Healthy controls

From: Association of salivary Cathepsin B in different histological grades among patients presenting with oral squamous cell carcinoma

Category

Healthy controls

N = 20 (%)

Well differentiated OSCC

N = 20 (%)

Moderate differentiated OSCC

N = 20 (%)

Poorly differentiated OSCC

N = 20 (%)

p value

Age in years^

37.5 (19)

47.5 (16)

48 (20)

42 (19)

0.17Ã’

Gender

     

 Male

12 (21.8)

17 (30.9)

14 (25.5)

12 (21.8)

0.27*

 Female

8 (32)

3 (12)

6 (24)

8 (32)

Habits

     

 No Habits

20 (100)

0 (0)

0 (0)

0 (0)

_

 Pan/Naswar

0 (0)

7 (50)

4 (28.6)

3 (21.4)

 Guthka

0 (0)

2 (22.2)

3 (33.3)

4 (44.4)

 Betel Nuts

0 (0)

1 (10)

5 (50)

4 (40)

 Smoking

0 (0)

4 (36.4)

3 (27.3)

4 (36.4)

 ≥ Two habits

0 (0)

6 (37.5)

5 (31.3)

5 (31.3)

Frequency

     

 1–5/day

0 (0)

4 (25)

4 (25)

8 (50)

0.59**

 6–10/day

0 (0)

5 (41.7)

5 (41.7)

2 (16.7)

 11–15/day

0 (0)

8 (40)

7 (35)

5 (25)

 16–20/day

0 (0)

3 (25)

4 (33.3)

5 (41.7)

Duration

     

 < 5 years

0 (0)

3 (60)

1 (20)

1 (20)

0.84**

 5–10 years

0 (0)

4 (36.4)

3 (27.3)

4 (36.4)

 11–15 years

0 (0)

6 (26.1)

10 (43.5)

7 (30.4)

 16–20 years

0 (0)

7 (33.3)

6 (28.6)

8 (38.1)

Site

     

 Buccal mucosa

0 (0)

11 (35.5)

9 (29)

11 (35.5)

0.82**

 Tongue

0 (0)

3 (30)

4 (40)

3 (30)

 Lower buccal sulcus

0 (0)

2 (50)

2 (50)

0 (0)

 Lower lip

0 (0)

2 (66.7)

0 (0)

1 (33.3)

 Palate

0 (0)

1 (25)

2 (50)

1 (25)

 Retromolar area

0 (0)

1 (20)

1 (20)

3 (60)

 Upper sulcus

0 (0)

0 (0)

2 (66.7)

1 (33.3)

  1. ^Values represented as Median (Interquartile Range)
  2. *Chi-Square
  3. **Fisher Exact test
  4. Ã’Kruskal Wallis Test