Table 3 ACE haplotypes frequencies in patients with RAS and controls
ACE | Haplotypes | Controls | RAS | P value | OR (CI 95%) | Controls | RAS | P value | OR (CI 95%) | Controls | RAS | P value | OR (CI 95%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N = 143 (%) | N = 87 (%) | Men | Men | Women | Women | ||||||||
N = 65 (%) | N = 34 (%) | N = 78 (%) | N = 53 (%) | ||||||||||
rs4311/rs4331/rs1799752 (I/D) | CGI | 46.5 | 31.5* | 0.005 | 0.575 (0.389–0.851) | 48.5 | 36.6 | 0.168 | 0.658 (0.362–1.197) | 44.9 | 28.5* | 0.016 | 0.531 (0.316–0.895) |
TAD | 43.0 | 36.5 | 0.479 | 0.871 (0.593–1.278) | 41.5 | 27.0 | 0.139 | 0.629 (0.338–1.171) | 44.2 | 42.6 | 0.866 | 1.043 (0.635–1.714) | |
CAD | 8.4 | 11.7 | 0.617 | 1.182 (0.616–2.269) | 9.2 | 13.6 | 0.810 | 1.128 (0.423–3.013) | 7.7 | 10.9 | 0.618 | 1.250 (0.519–3.008) | |
TAI | 1.1 | 0.0 | NA | 0 (0.000–0.000) | 0.0 | 0.0 | NA | 0 (0.000–0.000) | 1.9 | 0.0 | NA | 0 (0.000–0.000) | |
CGD | 0.7 | 1.0 | 0.150 | 3.341 (0.606–18.437) | 0.8 | 2.1 | 0.093 | 5.954 (0.607–58.370) | 0.7 | 0.0 | 0.784 | 1.476 (0.091–23.864) | |
TGD | 0.3 | 10.5* | < 0.00001 | 24.938 (3.249–191.404) | 0.0 | 14.6* | NA | 0 (0.000–0.000) | 0.6 | 7.8* | 0.012 | 9.300 (1.103–78.408) | |
CAI | 0.0 | 5.8 | NA | 0 (0.000–0.000) | 0.0 | 2.0 | NA | 0 (0.000–0.000) | 0.0 | 7.8 | NA | 0 (0.000–0.000) | |
TGI | 0.0 | 3.0 | NA | 0 (0.000–0.000) | 0.0 | 4.0 | NA | 0 (0.000–0.000) | 0.0 | 2.4 | NA | 0 (0.000–0.000) |