Group | 1st hour | 1st day | 7th day | 14th day | 21st day | **p-value |
---|---|---|---|---|---|---|
1 | 5.012 ± 0.807a (0.0107) | 11.747 ± 0.970b (0.0250) | 7.883 ± 1.153a (0.0168) | 2.081 ± 0.356c (0.0044) | 1.852 ± 0.190c (0.0039) | < 0.001 |
2 | 6.910 ± 1.445ab (0.0147) | 13.934 ± 2.208a (0.0296) | 9.112 ± 1.475b (0.0194) | 3.038 ± 0.454c (0.0065) | 2.302 ± 0.253d (0.0049) | < 0.001 |
3 | 7.411 ± 1.445ab (0.0157) | 13.008 ± 1.869a (0.0276) | 8.806 ± 2.051b (0.0187) | 2.603 ± 0.676c (0.0055) | 2.194 ± 0.373c (0.0047) | < 0.001 |
4 | 3.885 ± 0.331a (0.0083) | 8.947 ± 0.787b (0.0190) | 5.689 ± 0.417c (0.0125) | 1.568 ± 0.148d (0.0033) | 1.548 ± 0.190d (0.0033) | < 0.001 |
5 | 27.371 ± 7.976ab (0.0582) | 28.431 ± 5.619a (0.0604) | 14.340 ± 2.335b (0.0305) | 3.283 ± 0.332c (0.0070) | 2.034 ± 0.186d (0.0043) | < 0.001 |
6 | 4.213 ± 1.058a (0.0090) | 8.902 ± 1.058b (0.0189) | 5.895 ± 0.843a (0.0125) | 1.706 ± 0.393c (0.0036) | 1.606 ± 0.275c (0.0034) | < 0.001 |
7 | 2.543 ± 0.730a (0.0054) | 6.320 ± 0.638b (0.0134) | 3.842 ± 0.538c (0.0082) | 0.975 ± 0.204d (0.0021) | 1.075 ± 0.160d (0.0023) | < 0.001 |
8 | 2.735 ± 0.270a (0.0058) | 7.199 ± 0.501b (0.0153) | 4.290 ± 0.325c (0.0091) | 1.019 ± 0.119d (0.0022) | 0.972 ± 0.073d (0.0021) | < 0.001 |
9 | 2.107 ± 0.493a (0.0045) | 4.936 ± 1.067b (0.0105) | 3.355 ± 0.781ab (0.0071) | 0.800 ± 0.144c (0.0017) | 0.834 ± 0.131c (0.0018) | < 0.001 |
10 | 0.558 ± 0.117ac (0.0045) | 0.858 ± 0.215a (0.0018) | 1.116 ± 0.122b (0.0024) | 0.296 ± 0.037c (0.0006) | 0.000 ± 0.000d (0.0000) | < 0.001 |
11 | 2.495 ± 0.544a (0.0053) | 5.806 ± 0.334b (0.0123) | 4.329 ± 0.526b (0.0092) | 1.101 ± 0.103c (0.0023) | 1.068 ± 0.073c (0.0023) | < 0.001 |
12 | 0.232 ± 0.075ac (0.0005) | 0.355 ± 0.086a (0.0008) | 0.788 ± 0.142b (0.0017) | 0.204 ± 0.067c (0.0004) | 0.000 ± 0.000d (0.000) | < 0.001 |
*p-value | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |