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Table 3 Uni- and multivariable analysis of outcomes

From: Postoperative radiotherapy may not be necessary for locally advanced head and neck squamous cell carcinoma: a case-match multicentre study

  OS
RR (95% CI)
P DFS
RR (95% CI)
P
Age 0.989 (0.961–1.019) 0.472 1.000 (0.974–1.027) 0.993
Gender 2.013 (0.278–14.603) 0.489 2.302 (0.318–16.664) 0.409
Smoking 0.646 (0.345–1.207) 0.171 0.784 (0.425–1.446) 0.435
Alcohol 0.828 (0.468–1.468) 0.296 0.878 (0.509–1.512) 0.638
Subsite 1.331 (1.063–1.667) 0.013 1.345 (1.084–1.669) 0.007
T stage 1.129 (0.674–1.892) 0.645 1.036 (0.632–1.701) 0.887
Lymph node 1.638 (1.164–2.305) 0.005 1.726 (1.241–2.400) 0.001
Pathological grade 1.420 (0.769–2.623) 0.263 1.700 (0.933–3.100) 0.083
Postoperation radiotherapy 1.129 (0.636–2.002) 0.679 1.158 (0.671–1.997) 0.599
Adjuvant chemotherapy 0.587 (0.283–1.215) 0.130 0.483 (0.248–0.943) 0.033
Multivariable
 Subsite 1.457 (1.122–1.890) 0.005 1.423 (1.104–1.834) 0.006
 Lymph node 1.628 (1.143–2.317) 0.007 1.725 (1.227–2.424) 0.002
 Pathological grade 1.383 (0.734–2.605) 0.316 1.590 (0.851–2.970) 0.146
 Postoperation radiotherapy 1.184 (0.649–2.162) 0.582 1.169 (0.659–2.073) 0.594
 Adjuvant chemotherapy 0.647 (0.298–1.406) 0.272 0.579 (0.283–1.186) 0.135