Fig. 1
From: Molecular and oral manifestations of langerhans cell histiocytosis preceding acute myeloid leukemia
Clinical presentation and histopathologic findings of LCH. a Intraoral examination shows multiple ulcers and suppurations on the whole gingival mucosa and left hard-palate, with teeth loss; b Skin biopsy shows the intense proliferation of histiocytes, significant eosinophils and lymphocytes infiltrating (HE, × 600); Positive immunohistochemistry for c CD-1a, d S-100 and e CD163 in oral tissue (IHC, × 200); f Oral condition after one month of treatment HE Hematoxylin and eosin stain; IHC Immunohistochemistry stain