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Fig. 4 | BMC Oral Health

Fig. 4

From: MicroRNA-18a regulates the metastatic properties of oral squamous cell carcinoma cells via HIF-1α expression

Fig. 4

Cell viability, migration, and invasion abilities in OSCC cell lines according to miRNA-18a treatment. A Representative images acquired after an EdU assay in YD-10B and HSC-2 cells with and without miRNA-18a treatment (scale bar: 200 μm; original magnification: × 10). B Graphs showing the mean positive cell number for proliferation in five random regions in each well in the two tested OSCC cell lines. C Graphs showing cell viability, as measured using an MTT assay in YD-10B and HSC-2 cells. Representative images of D migration ability (scale bar: 200 μm; original magnification: × 10) and E invasion ability (scale bar: 200 μm; original magnification: × 20) in YD-10B and HSC-2 cells transfected with miRNA-18a. Graphs represent the mean migrated and invaded cells induced by miRNA-18a treatment in YD-10B and HSC-2 cells in five random regions in each well (bottom panels). *Significant difference between the control- and miRNA-18a-treated conditions (p < 0.05). miR-18a, microRNA-18a

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BMC Oral Health

ISSN: 1472-6831

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