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Table 2 Results of the immunofluorescence analysis for CD3, CD4, CD8, CLA, and E-selectin comparing GOLP and GORL

From: Lymphocyte and CD62E expression in lichen planus and lichenoid reaction

Immunostaining

Total number of lymphocytes

p *

d

GOLP

GORL

CD3+ §

25,832

13,469

0.311

0.343

CD3 + CD4+ ¥

15,678

6,510

0.615

0.127

CD3 + CD4+/CD3+ §

68,74

54,45

0.027

0.794

CD3 + CD8+ §

18,983

5,918

0.099

0.571

CD3 + CD8+/CD3+ §

67,91

51,74

0.038

0.738

CLA+ ¥

16,176

8,296

0.840

0.363

CD4 + CLA+ ¥

9,594

4,954

0.888

0.351

CLA+/CD4+ §

72,81

81,77

0.164

0.477

CD4 + CLA+/CD4+ ¥

42,57

49,17

0.618

0.405

CD8 + CLA+ §

7,856

4,908

0.089

0.591

CLA+/CD8+ §

78,09

58,85

0.420

0.271

CD8 + CLA+/CD8+ ¥

37,17

20,39

0.767

0.550

E-selectin §

1,217

539

0.892

0.046

  1. ¥ Student’s t-test; § Mann-Whitney Test; * p-value (p ≤ 0.05); GOLP: group of oral lichen planus; GORL: group of oral lichenoid reaction. “d” refers to effect size: no effect (d ≤ 0.1), small (0.20 ≤ d ≤ 0.40), medium (0.50 ≤ d ≤ 0.70), and large (d ≥ 0.80)