Fig. 1
From: Advances in novel therapeutic approaches for periodontal diseases
Overview of periodontal disease and factor that affects susceptibility to periodontal infections. Periodontal pathogens use an array of virulence factors to initiate periodontal disease. These virulence factors help the pathogens escape host cells' immune response. The progression of periodontal disease depends on the host’s response to microbial dysbiosis in biofilms. The severity and extent of periodontal disease are also influenced by host-specific, genetic, and environmental factors [7]