Fig. 2
From: Advances in novel therapeutic approaches for periodontal diseases
Flowchart of the literature search strategy and selection criteria. The literatures were retrieved from two databases: PubMed and Scopus. Search terms used in two separate searches includes: 1. (periodontal) AND (antibiotic) OR (virulence) OR (biofilm) OR (immunomodulatory AND therapy) OR (probiotic) OR (quorum AND sensing); 2. (periodontal* AND disease) AND (therapeutic*) AND (antibiotics OR antimicrobials) AND NOT (regenerative) AND NOT (rat or animal) AND NOT (case AND reports). The literatures were limited to articles published in English and within 15 years (2008–2022), while those of animal studies, case studies, or presented in the form of abstracts were excluded. 215 references relevant to the topics were cited in this review